(define (problem Pathways-08)
(:domain Pathways-ComplexPreferences)
(:objects
	Wee1 - simple
	SP1 - simple
	Skp2 - simple
	Skp1 - simple
	RPA - simple
	pRbp2 - simple
	pRb-E2F4p1-DP12 - simple
	pRb - simple
	p68 - simple
	p53p1 - simple
	p53 - simple
	p16 - simple
	m1433 - simple
	Jun - simple
	HDAC1 - simple
	gP - simple
	gERCC1 - simple
	E2F6 - simple
	E2F5 - simple
	E2F4 - simple
	E2F3 - simple
	E2F2 - simple
	E2F13p1-DP12p1 - simple
	E2F13p1-DP12 - simple
	E2F13-DP12 - simple
	E2F1 - simple
	DP12 - simple
	cycH - simple
	cycB - simple
	C-TAK1 - simple
	cks1 - simple
	CEBP - simple
	cdk7 - simple
	cdk46p3-cycDp1 - simple
	cdk46p3-cycD - simple
	cdk46p1 - simple
	cdk2p1 - simple
	cdk2-cycB - simple
	cdk2 - simple
	cdk1p1p2 - simple
	cdc25C - simple
	cdk1p1p2-cks1 - complex
	cdk1p1p2-Gadd45 - complex
	cdk1p1p2p3-cks1 - complex
	cdk1p1p2p3-Gadd45 - complex
	cdk1p1p2p3 - complex
	cdk1p1p2p3-cycA - complex
	cdk1p1p2p3-cycB - complex
	cdk2-cks1 - complex
	cdk2p1-cycB - complex
	cdk2p1-cks1 - complex
	cdk2p1p2-cks1 - complex
	cdk2p1p2 - complex
	cdk2p2-cks1 - complex
	cdk2p2 - complex
	cdk7-cycH - complex
	cdk7p1-cycH - complex
	CEBP-gP - complex
	CEBP-pRb - complex
	CEBP-pRb-gP - complex
	CEBP-pRbp1 - complex
	CEBP-pRbp1-gP - complex
	CEBP-pRbp1p2 - complex
	CEBP-pRbp1p2-gP - complex
	CEBP-pRbp2 - complex
	P - complex
	CEBP-pRbp2-gP - complex
	E2F1-DP12 - complex
	E2F2-DP12 - complex
	E2F3-DP12 - complex
	E2F6-DP12 - complex
	HDAC1-p107-E2F4-DP12 - complex
	HDAC1-pRb-E2F13-DP12 - complex
	HDAC1-pRb-E2F13p1-DP12 - complex
	HDAC1-pRb-E2F13p1-DP12p1 - complex
	HDAC1-pRb-E2F4-DP12 - complex
	HDAC1-pRb-E2F4p1-DP12 - complex
	Jun-c-Fos-gERCC1 - complex
	Jun-c-Fos - complex
	m1433-cdc25Cp2 - complex
	cdc25Cp2 - complex
	Mdm2-E2F13-DP12 - complex
	Mdm2-E2F13p1-DP12 - complex
	Mdm2-E2F13p1-DP12p1 - complex
	Mdm2-pRb - complex
	Mdm2-pRbp1 - complex
	Mdm2-pRbp1p2 - complex
	Mdm2-pRbp2 - complex
	p107-E2F4-DP12 - complex
	E2F5-DP12 - complex
	p16-cdk46p1 - complex
	p16-cdk46p1p2 - complex
	cdk46p1p2 - complex
	p16-cdk7 - complex
	p16-cdk7p1 - complex
	cdk7p1 - complex
	p21-cdk2-cycA - complex
	p21-cdk2-cycEp1 - complex
	p21-cdk2-cycE - complex
	p21-cdk2p1-cycA - complex
	p21-cdk2p1-cycEp1 - complex
	p21-cdk2p1-cycE - complex
	p21-cdk2p1p2-cycA - complex
	p21-cdk2p1p2-cycEp1 - complex
	p21-cdk2p1p2-cycE - complex
	p21-cdk2p2-cycA - complex
	p21-cdk2p2-cycEp1 - complex
	p21-cdk2p2-cycE - complex
	p21-cdk46p1-cycDp1 - complex
	p21-cdk46p1-cycD - complex
	p21-cdk46p1p2-cycDp1 - complex
	p21-cdk46p1p2-cycD - complex
	p21-Gadd45 - complex
	p53-DP12p1 - complex
	p53-DP12 - complex
	p53p1-DP12p1 - complex
	DP12p1 - complex
	p53p1-DP12 - complex
	Mdm2 - complex
	p68p1 - complex
	p68p1p2 - complex
	p68p2 - complex
	Gadd45 - complex
	cdk2-cycEp1 - complex
	cdk2-cycE - complex
	cdk2p1-cycEp1 - complex
	cdk2p1-cycE - complex
	cdk2p1p2-cycEp1 - complex
	cdk2p1p2-cycE - complex
	cdk46p1-cycDp1 - complex
	cdk46p1-cycD - complex
	cdk46p1p2-cycDp1 - complex
	cdk46p1p2-cycD - complex
	p21 - complex
	pRb-Jun-c-Fos-gERCC1 - complex
	pRb-Jun-c-Fos - complex
	pRb-Jun - complex
	cdk2p2-cycEp1 - complex
	cdk2p2-cycE - complex
	E2F4-DP12 - complex
	pRbp1-Jun-c-Fos-gERCC1 - complex
	pRbp1-Jun-c-Fos - complex
	pRbp1-Jun - complex
	pRbp1 - complex
	pRbp1p2-Jun-c-Fos-gERCC1 - complex
	pRbp1p2-Jun-c-Fos - complex
	pRbp1p2-Jun - complex
	pRbp1p2 - complex
	ERCC1 - complex
	pRbp2-Jun-c-Fos-gERCC1 - complex
	pRbp2-Jun-c-Fos - complex
	c-Fos - complex
	pRbp2-Jun - complex
	pRb-E2F13-DP12 - complex
	pRb-E2F13p1-DP12p1 - complex
	pRb-E2F13p1-DP12 - complex
	pRb-E2F4-DP12 - complex
	pRbp1-E2F13-DP12 - complex
	pRbp1-E2F13p1-DP12p1 - complex
	pRbp1-E2F13p1-DP12 - complex
	pRbp1-E2F4-DP12 - complex
	RPA-cycA - complex
	Skp2-cdk2-cycA - complex
	Skp2-cdk2p1-cycA - complex
	Skp2-cdk2p1p2-cycA - complex
	Skp2-cdk2p2-cycA - complex
	Skp2p1-Skp1p1 - complex
	Skp2p1-Skp1 - complex
	Skp2p1 - complex
	Skp2-Skp1-cdk2-cycA - complex
	Skp2-Skp1-cdk2p1-cycA - complex
	Skp2-Skp1-cdk2p1p2-cycA - complex
	Skp2-Skp1-cdk2p2-cycA - complex
	Skp2-Skp1p1-cdk2-cycA - complex
	cdk2-cycA - complex
	Skp2-Skp1p1-cdk2p1-cycA - complex
	cdk2p1-cycA - complex
	Skp2-Skp1p1-cdk2p1p2-cycA - complex
	cdk2p1p2-cycA - complex
	Skp2-Skp1p1-cdk2p2-cycA - complex
	cdk2p2-cycA - complex
	Skp2-Skp1p1 - complex
	Skp1p1 - complex
	Skp2-Skp1 - complex
	c-Myc - complex
	cycA - complex
	cycD - complex
	cycDp1 - complex
	cycE - complex
	cycEp1 - complex
	p19ARF - complex
	pol - complex
	SP1-gP - complex
	SP1-p107-gP - complex
	SP1-p107p1-gP - complex
	SP1-p107p1 - complex
	p107p1 - complex
	SP1-p107 - complex
	p107 - complex)


(:init
	(possible Wee1)
	(= (available Wee1) 0)
	(possible SP1)
	(= (available SP1) 0)
	(possible Skp2)
	(= (available Skp2) 0)
	(possible Skp1)
	(= (available Skp1) 0)
	(possible RPA)
	(= (available RPA) 0)
	(possible pRbp2)
	(= (available pRbp2) 0)
	(possible pRb-E2F4p1-DP12)
	(= (available pRb-E2F4p1-DP12) 0)
	(possible pRb)
	(= (available pRb) 0)
	(possible p68)
	(= (available p68) 0)
	(possible p53p1)
	(= (available p53p1) 0)
	(possible p53)
	(= (available p53) 0)
	(possible p16)
	(= (available p16) 0)
	(possible m1433)
	(= (available m1433) 0)
	(possible Jun)
	(= (available Jun) 0)
	(possible HDAC1)
	(= (available HDAC1) 0)
	(possible gP)
	(= (available gP) 0)
	(possible gERCC1)
	(= (available gERCC1) 0)
	(possible E2F6)
	(= (available E2F6) 0)
	(possible E2F5)
	(= (available E2F5) 0)
	(possible E2F4)
	(= (available E2F4) 0)
	(possible E2F3)
	(= (available E2F3) 0)
	(possible E2F2)
	(= (available E2F2) 0)
	(possible E2F13p1-DP12p1)
	(= (available E2F13p1-DP12p1) 0)
	(possible E2F13p1-DP12)
	(= (available E2F13p1-DP12) 0)
	(possible E2F13-DP12)
	(= (available E2F13-DP12) 0)
	(possible E2F1)
	(= (available E2F1) 0)
	(possible DP12)
	(= (available DP12) 0)
	(possible cycH)
	(= (available cycH) 0)
	(possible cycB)
	(= (available cycB) 0)
	(possible C-TAK1)
	(= (available C-TAK1) 0)
	(possible cks1)
	(= (available cks1) 0)
	(possible CEBP)
	(= (available CEBP) 0)
	(possible cdk7)
	(= (available cdk7) 0)
	(possible cdk46p3-cycDp1)
	(= (available cdk46p3-cycDp1) 0)
	(possible cdk46p3-cycD)
	(= (available cdk46p3-cycD) 0)
	(possible cdk46p1)
	(= (available cdk46p1) 0)
	(possible cdk2p1)
	(= (available cdk2p1) 0)
	(possible cdk2-cycB)
	(= (available cdk2-cycB) 0)
	(possible cdk2)
	(= (available cdk2) 0)
	(possible cdk1p1p2)
	(= (available cdk1p1p2) 0)
	(possible cdc25C)
	(= (available cdc25C) 0)
	(= (available cdk1p1p2-cks1) 0)
	(= (available cdk1p1p2-Gadd45) 0)
	(= (available cdk1p1p2p3-cks1) 0)
	(= (available cdk1p1p2p3-Gadd45) 0)
	(= (available cdk1p1p2p3) 0)
	(= (available cdk1p1p2p3-cycA) 0)
	(= (available cdk1p1p2p3-cycB) 0)
	(= (available cdk2-cks1) 0)
	(= (available cdk2p1-cycB) 0)
	(= (available cdk2p1-cks1) 0)
	(= (available cdk2p1p2-cks1) 0)
	(= (available cdk2p1p2) 0)
	(= (available cdk2p2-cks1) 0)
	(= (available cdk2p2) 0)
	(= (available cdk7-cycH) 0)
	(= (available cdk7p1-cycH) 0)
	(= (available CEBP-gP) 0)
	(= (available CEBP-pRb) 0)
	(= (available CEBP-pRb-gP) 0)
	(= (available CEBP-pRbp1) 0)
	(= (available CEBP-pRbp1-gP) 0)
	(= (available CEBP-pRbp1p2) 0)
	(= (available CEBP-pRbp1p2-gP) 0)
	(= (available CEBP-pRbp2) 0)
	(= (available P) 0)
	(= (available CEBP-pRbp2-gP) 0)
	(= (available E2F1-DP12) 0)
	(= (available E2F2-DP12) 0)
	(= (available E2F3-DP12) 0)
	(= (available E2F6-DP12) 0)
	(= (available HDAC1-p107-E2F4-DP12) 0)
	(= (available HDAC1-pRb-E2F13-DP12) 0)
	(= (available HDAC1-pRb-E2F13p1-DP12) 0)
	(= (available HDAC1-pRb-E2F13p1-DP12p1) 0)
	(= (available HDAC1-pRb-E2F4-DP12) 0)
	(= (available HDAC1-pRb-E2F4p1-DP12) 0)
	(= (available Jun-c-Fos-gERCC1) 0)
	(= (available Jun-c-Fos) 0)
	(= (available m1433-cdc25Cp2) 0)
	(= (available cdc25Cp2) 0)
	(= (available Mdm2-E2F13-DP12) 0)
	(= (available Mdm2-E2F13p1-DP12) 0)
	(= (available Mdm2-E2F13p1-DP12p1) 0)
	(= (available Mdm2-pRb) 0)
	(= (available Mdm2-pRbp1) 0)
	(= (available Mdm2-pRbp1p2) 0)
	(= (available Mdm2-pRbp2) 0)
	(= (available p107-E2F4-DP12) 0)
	(= (available E2F5-DP12) 0)
	(= (available p16-cdk46p1) 0)
	(= (available p16-cdk46p1p2) 0)
	(= (available cdk46p1p2) 0)
	(= (available p16-cdk7) 0)
	(= (available p16-cdk7p1) 0)
	(= (available cdk7p1) 0)
	(= (available p21-cdk2-cycA) 0)
	(= (available p21-cdk2-cycEp1) 0)
	(= (available p21-cdk2-cycE) 0)
	(= (available p21-cdk2p1-cycA) 0)
	(= (available p21-cdk2p1-cycEp1) 0)
	(= (available p21-cdk2p1-cycE) 0)
	(= (available p21-cdk2p1p2-cycA) 0)
	(= (available p21-cdk2p1p2-cycEp1) 0)
	(= (available p21-cdk2p1p2-cycE) 0)
	(= (available p21-cdk2p2-cycA) 0)
	(= (available p21-cdk2p2-cycEp1) 0)
	(= (available p21-cdk2p2-cycE) 0)
	(= (available p21-cdk46p1-cycDp1) 0)
	(= (available p21-cdk46p1-cycD) 0)
	(= (available p21-cdk46p1p2-cycDp1) 0)
	(= (available p21-cdk46p1p2-cycD) 0)
	(= (available p21-Gadd45) 0)
	(= (available p53-DP12p1) 0)
	(= (available p53-DP12) 0)
	(= (available p53p1-DP12p1) 0)
	(= (available DP12p1) 0)
	(= (available p53p1-DP12) 0)
	(= (available Mdm2) 0)
	(= (available p68p1) 0)
	(= (available p68p1p2) 0)
	(= (available p68p2) 0)
	(= (available Gadd45) 0)
	(= (available cdk2-cycEp1) 0)
	(= (available cdk2-cycE) 0)
	(= (available cdk2p1-cycEp1) 0)
	(= (available cdk2p1-cycE) 0)
	(= (available cdk2p1p2-cycEp1) 0)
	(= (available cdk2p1p2-cycE) 0)
	(= (available cdk46p1-cycDp1) 0)
	(= (available cdk46p1-cycD) 0)
	(= (available cdk46p1p2-cycDp1) 0)
	(= (available cdk46p1p2-cycD) 0)
	(= (available p21) 0)
	(= (available pRb-Jun-c-Fos-gERCC1) 0)
	(= (available pRb-Jun-c-Fos) 0)
	(= (available pRb-Jun) 0)
	(= (available cdk2p2-cycEp1) 0)
	(= (available cdk2p2-cycE) 0)
	(= (available E2F4-DP12) 0)
	(= (available pRbp1-Jun-c-Fos-gERCC1) 0)
	(= (available pRbp1-Jun-c-Fos) 0)
	(= (available pRbp1-Jun) 0)
	(= (available pRbp1) 0)
	(= (available pRbp1p2-Jun-c-Fos-gERCC1) 0)
	(= (available pRbp1p2-Jun-c-Fos) 0)
	(= (available pRbp1p2-Jun) 0)
	(= (available pRbp1p2) 0)
	(= (available ERCC1) 0)
	(= (available pRbp2-Jun-c-Fos-gERCC1) 0)
	(= (available pRbp2-Jun-c-Fos) 0)
	(= (available c-Fos) 0)
	(= (available pRbp2-Jun) 0)
	(= (available pRb-E2F13-DP12) 0)
	(= (available pRb-E2F13p1-DP12p1) 0)
	(= (available pRb-E2F13p1-DP12) 0)
	(= (available pRb-E2F4-DP12) 0)
	(= (available pRbp1-E2F13-DP12) 0)
	(= (available pRbp1-E2F13p1-DP12p1) 0)
	(= (available pRbp1-E2F13p1-DP12) 0)
	(= (available pRbp1-E2F4-DP12) 0)
	(= (available RPA-cycA) 0)
	(= (available Skp2-cdk2-cycA) 0)
	(= (available Skp2-cdk2p1-cycA) 0)
	(= (available Skp2-cdk2p1p2-cycA) 0)
	(= (available Skp2-cdk2p2-cycA) 0)
	(= (available Skp2p1-Skp1p1) 0)
	(= (available Skp2p1-Skp1) 0)
	(= (available Skp2p1) 0)
	(= (available Skp2-Skp1-cdk2-cycA) 0)
	(= (available Skp2-Skp1-cdk2p1-cycA) 0)
	(= (available Skp2-Skp1-cdk2p1p2-cycA) 0)
	(= (available Skp2-Skp1-cdk2p2-cycA) 0)
	(= (available Skp2-Skp1p1-cdk2-cycA) 0)
	(= (available cdk2-cycA) 0)
	(= (available Skp2-Skp1p1-cdk2p1-cycA) 0)
	(= (available cdk2p1-cycA) 0)
	(= (available Skp2-Skp1p1-cdk2p1p2-cycA) 0)
	(= (available cdk2p1p2-cycA) 0)
	(= (available Skp2-Skp1p1-cdk2p2-cycA) 0)
	(= (available cdk2p2-cycA) 0)
	(= (available Skp2-Skp1p1) 0)
	(= (available Skp1p1) 0)
	(= (available Skp2-Skp1) 0)
	(= (available c-Myc) 0)
	(= (available cycA) 0)
	(= (available cycD) 0)
	(= (available cycDp1) 0)
	(= (available cycE) 0)
	(= (available cycEp1) 0)
	(= (available p19ARF) 0)
	(= (available pol) 0)
	(= (available SP1-gP) 0)
	(= (available SP1-p107-gP) 0)
	(= (available SP1-p107p1-gP) 0)
	(= (available SP1-p107p1) 0)
	(= (available p107p1) 0)
	(= (available SP1-p107) 0)
	(= (available p107) 0)
	(catalyzed-association-reaction cdc25C C-TAK1 cdc25Cp2)
	(= (need-for-catalyzed-association cdc25C C-TAK1 cdc25Cp2) 2)
	(= (need-for-catalyzed-association C-TAK1 cdc25C cdc25Cp2) 3)
	(= (prod-by-catalyzed-association cdc25C C-TAK1 cdc25Cp2) 3)
	(catalyzed-association-reaction cdk1p1p2 cdk7-cycH cdk1p1p2p3)
	(= (need-for-catalyzed-association cdk1p1p2 cdk7-cycH cdk1p1p2p3) 1)
	(= (need-for-catalyzed-association cdk7-cycH cdk1p1p2 cdk1p1p2p3) 2)
	(= (prod-by-catalyzed-association cdk1p1p2 cdk7-cycH cdk1p1p2p3) 2)
	(association-reaction cdk1p1p2 cks1 cdk1p1p2-cks1)
	(= (need-for-association cdk1p1p2 cks1 cdk1p1p2-cks1) 1)
	(= (need-for-association cks1 cdk1p1p2 cdk1p1p2-cks1) 1)
	(= (prod-by-association cdk1p1p2 cks1 cdk1p1p2-cks1) 4)
	(association-reaction cdk1p1p2 Gadd45 cdk1p1p2-Gadd45)
	(= (need-for-association cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 1)
	(= (need-for-association Gadd45 cdk1p1p2 cdk1p1p2-Gadd45) 4)
	(= (prod-by-association cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 2)
	(association-reaction cdk1p1p2p3 cks1 cdk1p1p2p3-cks1)
	(= (need-for-association cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 4)
	(= (need-for-association cks1 cdk1p1p2p3 cdk1p1p2p3-cks1) 1)
	(= (prod-by-association cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 1)
	(association-reaction cdk1p1p2p3 cycA cdk1p1p2p3-cycA)
	(= (need-for-association cdk1p1p2p3 cycA cdk1p1p2p3-cycA) 1)
	(= (need-for-association cycA cdk1p1p2p3 cdk1p1p2p3-cycA) 1)
	(= (prod-by-association cdk1p1p2p3 cycA cdk1p1p2p3-cycA) 1)
	(association-reaction cdk1p1p2p3 cycB cdk1p1p2p3-cycB)
	(= (need-for-association cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 1)
	(= (need-for-association cycB cdk1p1p2p3 cdk1p1p2p3-cycB) 4)
	(= (prod-by-association cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 4)
	(association-reaction cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45)
	(= (need-for-association cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 3)
	(= (need-for-association Gadd45 cdk1p1p2p3 cdk1p1p2p3-Gadd45) 1)
	(= (prod-by-association cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 2)
	(catalyzed-association-reaction cdk2 cdk7-cycH cdk2p2)
	(= (need-for-catalyzed-association cdk2 cdk7-cycH cdk2p2) 3)
	(= (need-for-catalyzed-association cdk7-cycH cdk2 cdk2p2) 4)
	(= (prod-by-catalyzed-association cdk2 cdk7-cycH cdk2p2) 3)
	(association-reaction cdk2 cks1 cdk2-cks1)
	(= (need-for-association cdk2 cks1 cdk2-cks1) 2)
	(= (need-for-association cks1 cdk2 cdk2-cks1) 2)
	(= (prod-by-association cdk2 cks1 cdk2-cks1) 1)
	(association-reaction cdk2 cycA cdk2-cycA)
	(= (need-for-association cdk2 cycA cdk2-cycA) 3)
	(= (need-for-association cycA cdk2 cdk2-cycA) 3)
	(= (prod-by-association cdk2 cycA cdk2-cycA) 3)
	(catalyzed-association-reaction cdk2-cycA cdk7-cycH cdk2p2-cycA)
	(= (need-for-catalyzed-association cdk2-cycA cdk7-cycH cdk2p2-cycA) 1)
	(= (need-for-catalyzed-association cdk7-cycH cdk2-cycA cdk2p2-cycA) 3)
	(= (prod-by-catalyzed-association cdk2-cycA cdk7-cycH cdk2p2-cycA) 4)
	(catalyzed-association-reaction cdk2-cycA Wee1 cdk2p1-cycA)
	(= (need-for-catalyzed-association cdk2-cycA Wee1 cdk2p1-cycA) 2)
	(= (need-for-catalyzed-association Wee1 cdk2-cycA cdk2p1-cycA) 3)
	(= (prod-by-catalyzed-association cdk2-cycA Wee1 cdk2p1-cycA) 4)
	(catalyzed-association-reaction cdk2-cycB Wee1 cdk2p1-cycB)
	(= (need-for-catalyzed-association cdk2-cycB Wee1 cdk2p1-cycB) 1)
	(= (need-for-catalyzed-association Wee1 cdk2-cycB cdk2p1-cycB) 3)
	(= (prod-by-catalyzed-association cdk2-cycB Wee1 cdk2p1-cycB) 4)
	(association-reaction cdk2 cycE cdk2-cycE)
	(= (need-for-association cdk2 cycE cdk2-cycE) 2)
	(= (need-for-association cycE cdk2 cdk2-cycE) 2)
	(= (prod-by-association cdk2 cycE cdk2-cycE) 4)
	(catalyzed-association-reaction cdk2-cycE cdk7-cycH cdk2p2-cycE)
	(= (need-for-catalyzed-association cdk2-cycE cdk7-cycH cdk2p2-cycE) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk2-cycE cdk2p2-cycE) 3)
	(= (prod-by-catalyzed-association cdk2-cycE cdk7-cycH cdk2p2-cycE) 4)
	(association-reaction cdk2 cycEp1 cdk2-cycEp1)
	(= (need-for-association cdk2 cycEp1 cdk2-cycEp1) 2)
	(= (need-for-association cycEp1 cdk2 cdk2-cycEp1) 3)
	(= (prod-by-association cdk2 cycEp1 cdk2-cycEp1) 4)
	(catalyzed-association-reaction cdk2-cycEp1 cdk7-cycH cdk2p2-cycEp1)
	(= (need-for-catalyzed-association cdk2-cycEp1 cdk7-cycH cdk2p2-cycEp1) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk2-cycEp1 cdk2p2-cycEp1) 1)
	(= (prod-by-catalyzed-association cdk2-cycEp1 cdk7-cycH cdk2p2-cycEp1) 4)
	(catalyzed-association-reaction cdk2p1 cdk7-cycH cdk2p1p2)
	(= (need-for-catalyzed-association cdk2p1 cdk7-cycH cdk2p1p2) 3)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1 cdk2p1p2) 3)
	(= (prod-by-catalyzed-association cdk2p1 cdk7-cycH cdk2p1p2) 4)
	(association-reaction cdk2p1 cks1 cdk2p1-cks1)
	(= (need-for-association cdk2p1 cks1 cdk2p1-cks1) 2)
	(= (need-for-association cks1 cdk2p1 cdk2p1-cks1) 1)
	(= (prod-by-association cdk2p1 cks1 cdk2p1-cks1) 1)
	(association-reaction cdk2p1 cycA cdk2p1-cycA)
	(= (need-for-association cdk2p1 cycA cdk2p1-cycA) 2)
	(= (need-for-association cycA cdk2p1 cdk2p1-cycA) 3)
	(= (prod-by-association cdk2p1 cycA cdk2p1-cycA) 4)
	(catalyzed-association-reaction cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA)
	(= (need-for-catalyzed-association cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1-cycA cdk2p1p2-cycA) 3)
	(= (prod-by-catalyzed-association cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA) 2)
	(association-reaction cdk2p1 cycE cdk2p1-cycE)
	(= (need-for-association cdk2p1 cycE cdk2p1-cycE) 3)
	(= (need-for-association cycE cdk2p1 cdk2p1-cycE) 1)
	(= (prod-by-association cdk2p1 cycE cdk2p1-cycE) 1)
	(catalyzed-association-reaction cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE)
	(= (need-for-catalyzed-association cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE) 3)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1-cycE cdk2p1p2-cycE) 1)
	(= (prod-by-catalyzed-association cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE) 3)
	(association-reaction cdk2p1 cycEp1 cdk2p1-cycEp1)
	(= (need-for-association cdk2p1 cycEp1 cdk2p1-cycEp1) 2)
	(= (need-for-association cycEp1 cdk2p1 cdk2p1-cycEp1) 3)
	(= (prod-by-association cdk2p1 cycEp1 cdk2p1-cycEp1) 1)
	(catalyzed-association-reaction cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1)
	(= (need-for-catalyzed-association cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1) 1)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1-cycEp1 cdk2p1p2-cycEp1) 4)
	(= (prod-by-catalyzed-association cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1) 3)
	(association-reaction cdk2p1p2 cks1 cdk2p1p2-cks1)
	(= (need-for-association cdk2p1p2 cks1 cdk2p1p2-cks1) 1)
	(= (need-for-association cks1 cdk2p1p2 cdk2p1p2-cks1) 2)
	(= (prod-by-association cdk2p1p2 cks1 cdk2p1p2-cks1) 1)
	(association-reaction cdk2p1p2 cycA cdk2p1p2-cycA)
	(= (need-for-association cdk2p1p2 cycA cdk2p1p2-cycA) 4)
	(= (need-for-association cycA cdk2p1p2 cdk2p1p2-cycA) 3)
	(= (prod-by-association cdk2p1p2 cycA cdk2p1p2-cycA) 2)
	(association-reaction cdk2p1p2 cycE cdk2p1p2-cycE)
	(= (need-for-association cdk2p1p2 cycE cdk2p1p2-cycE) 3)
	(= (need-for-association cycE cdk2p1p2 cdk2p1p2-cycE) 1)
	(= (prod-by-association cdk2p1p2 cycE cdk2p1p2-cycE) 4)
	(association-reaction cdk2p1p2 cycEp1 cdk2p1p2-cycEp1)
	(= (need-for-association cdk2p1p2 cycEp1 cdk2p1p2-cycEp1) 2)
	(= (need-for-association cycEp1 cdk2p1p2 cdk2p1p2-cycEp1) 2)
	(= (prod-by-association cdk2p1p2 cycEp1 cdk2p1p2-cycEp1) 4)
	(association-reaction cdk2p2 cks1 cdk2p2-cks1)
	(= (need-for-association cdk2p2 cks1 cdk2p2-cks1) 3)
	(= (need-for-association cks1 cdk2p2 cdk2p2-cks1) 3)
	(= (prod-by-association cdk2p2 cks1 cdk2p2-cks1) 2)
	(association-reaction cdk2p2 cycA cdk2p2-cycA)
	(= (need-for-association cdk2p2 cycA cdk2p2-cycA) 2)
	(= (need-for-association cycA cdk2p2 cdk2p2-cycA) 2)
	(= (prod-by-association cdk2p2 cycA cdk2p2-cycA) 1)
	(catalyzed-association-reaction cdk2p2-cycA Wee1 cdk2p1p2-cycA)
	(= (need-for-catalyzed-association cdk2p2-cycA Wee1 cdk2p1p2-cycA) 3)
	(= (need-for-catalyzed-association Wee1 cdk2p2-cycA cdk2p1p2-cycA) 1)
	(= (prod-by-catalyzed-association cdk2p2-cycA Wee1 cdk2p1p2-cycA) 1)
	(association-reaction cdk2p2 cycE cdk2p2-cycE)
	(= (need-for-association cdk2p2 cycE cdk2p2-cycE) 3)
	(= (need-for-association cycE cdk2p2 cdk2p2-cycE) 3)
	(= (prod-by-association cdk2p2 cycE cdk2p2-cycE) 1)
	(association-reaction cdk2p2 cycEp1 cdk2p2-cycEp1)
	(= (need-for-association cdk2p2 cycEp1 cdk2p2-cycEp1) 2)
	(= (need-for-association cycEp1 cdk2p2 cdk2p2-cycEp1) 4)
	(= (prod-by-association cdk2p2 cycEp1 cdk2p2-cycEp1) 3)
	(catalyzed-association-reaction cdk46p1 cdk7-cycH cdk46p1p2)
	(= (need-for-catalyzed-association cdk46p1 cdk7-cycH cdk46p1p2) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk46p1 cdk46p1p2) 4)
	(= (prod-by-catalyzed-association cdk46p1 cdk7-cycH cdk46p1p2) 3)
	(association-reaction cdk46p1 cycD cdk46p1-cycD)
	(= (need-for-association cdk46p1 cycD cdk46p1-cycD) 4)
	(= (need-for-association cycD cdk46p1 cdk46p1-cycD) 4)
	(= (prod-by-association cdk46p1 cycD cdk46p1-cycD) 4)
	(catalyzed-association-reaction cdk46p1-cycD cdk7-cycH cdk46p1p2-cycD)
	(= (need-for-catalyzed-association cdk46p1-cycD cdk7-cycH cdk46p1p2-cycD) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk46p1-cycD cdk46p1p2-cycD) 3)
	(= (prod-by-catalyzed-association cdk46p1-cycD cdk7-cycH cdk46p1p2-cycD) 2)
	(association-reaction cdk46p1 cycDp1 cdk46p1-cycDp1)
	(= (need-for-association cdk46p1 cycDp1 cdk46p1-cycDp1) 1)
	(= (need-for-association cycDp1 cdk46p1 cdk46p1-cycDp1) 2)
	(= (prod-by-association cdk46p1 cycDp1 cdk46p1-cycDp1) 2)
	(catalyzed-association-reaction cdk46p1-cycDp1 cdk7-cycH cdk46p1p2-cycDp1)
	(= (need-for-catalyzed-association cdk46p1-cycDp1 cdk7-cycH cdk46p1p2-cycDp1) 1)
	(= (need-for-catalyzed-association cdk7-cycH cdk46p1-cycDp1 cdk46p1p2-cycDp1) 3)
	(= (prod-by-catalyzed-association cdk46p1-cycDp1 cdk7-cycH cdk46p1p2-cycDp1) 4)
	(association-reaction cdk46p1p2 cycD cdk46p1p2-cycD)
	(= (need-for-association cdk46p1p2 cycD cdk46p1p2-cycD) 4)
	(= (need-for-association cycD cdk46p1p2 cdk46p1p2-cycD) 1)
	(= (prod-by-association cdk46p1p2 cycD cdk46p1p2-cycD) 2)
	(association-reaction cdk46p1p2 cycDp1 cdk46p1p2-cycDp1)
	(= (need-for-association cdk46p1p2 cycDp1 cdk46p1p2-cycDp1) 2)
	(= (need-for-association cycDp1 cdk46p1p2 cdk46p1p2-cycDp1) 2)
	(= (prod-by-association cdk46p1p2 cycDp1 cdk46p1p2-cycDp1) 4)
	(catalyzed-association-reaction cdk7 cdk7-cycH cdk7p1)
	(= (need-for-catalyzed-association cdk7 cdk7-cycH cdk7p1) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk7 cdk7p1) 1)
	(= (prod-by-catalyzed-association cdk7 cdk7-cycH cdk7p1) 4)
	(association-reaction cdk7 cycH cdk7-cycH)
	(= (need-for-association cdk7 cycH cdk7-cycH) 2)
	(= (need-for-association cycH cdk7 cdk7-cycH) 3)
	(= (prod-by-association cdk7 cycH cdk7-cycH) 2)
	(catalyzed-association-reaction cdk7-cycH cdk7-cycH cdk7p1-cycH)
	(= (need-for-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 4)
	(= (prod-by-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 1)
	(association-reaction cdk7p1 cycH cdk7p1-cycH)
	(= (need-for-association cdk7p1 cycH cdk7p1-cycH) 1)
	(= (need-for-association cycH cdk7p1 cdk7p1-cycH) 1)
	(= (prod-by-association cdk7p1 cycH cdk7p1-cycH) 4)
	(association-reaction CEBP gP CEBP-gP)
	(= (need-for-association CEBP gP CEBP-gP) 3)
	(= (need-for-association gP CEBP CEBP-gP) 4)
	(= (prod-by-association CEBP gP CEBP-gP) 4)
	(synthesis-reaction CEBP-gP P) 
	(= (need-for-synthesis CEBP-gP P) 2)
	(= (prod-by-synthesis CEBP-gP P) 4)
	(association-reaction CEBP pRb CEBP-pRb)
	(= (need-for-association CEBP pRb CEBP-pRb) 2)
	(= (need-for-association pRb CEBP CEBP-pRb) 3)
	(= (prod-by-association CEBP pRb CEBP-pRb) 4)
	(association-reaction CEBP-pRb gP CEBP-pRb-gP)
	(= (need-for-association CEBP-pRb gP CEBP-pRb-gP) 3)
	(= (need-for-association gP CEBP-pRb CEBP-pRb-gP) 4)
	(= (prod-by-association CEBP-pRb gP CEBP-pRb-gP) 4)
	(synthesis-reaction CEBP-pRb-gP P) 
	(= (need-for-synthesis CEBP-pRb-gP P) 2)
	(= (prod-by-synthesis CEBP-pRb-gP P) 3)
	(association-reaction CEBP pRbp1 CEBP-pRbp1)
	(= (need-for-association CEBP pRbp1 CEBP-pRbp1) 4)
	(= (need-for-association pRbp1 CEBP CEBP-pRbp1) 2)
	(= (prod-by-association CEBP pRbp1 CEBP-pRbp1) 1)
	(association-reaction CEBP-pRbp1 gP CEBP-pRbp1-gP)
	(= (need-for-association CEBP-pRbp1 gP CEBP-pRbp1-gP) 1)
	(= (need-for-association gP CEBP-pRbp1 CEBP-pRbp1-gP) 4)
	(= (prod-by-association CEBP-pRbp1 gP CEBP-pRbp1-gP) 4)
	(synthesis-reaction CEBP-pRbp1-gP P) 
	(= (need-for-synthesis CEBP-pRbp1-gP P) 2)
	(= (prod-by-synthesis CEBP-pRbp1-gP P) 4)
	(association-reaction CEBP pRbp1p2 CEBP-pRbp1p2)
	(= (need-for-association CEBP pRbp1p2 CEBP-pRbp1p2) 3)
	(= (need-for-association pRbp1p2 CEBP CEBP-pRbp1p2) 3)
	(= (prod-by-association CEBP pRbp1p2 CEBP-pRbp1p2) 2)
	(association-reaction CEBP-pRbp1p2 gP CEBP-pRbp1p2-gP)
	(= (need-for-association CEBP-pRbp1p2 gP CEBP-pRbp1p2-gP) 4)
	(= (need-for-association gP CEBP-pRbp1p2 CEBP-pRbp1p2-gP) 4)
	(= (prod-by-association CEBP-pRbp1p2 gP CEBP-pRbp1p2-gP) 2)
	(synthesis-reaction CEBP-pRbp1p2-gP P) 
	(= (need-for-synthesis CEBP-pRbp1p2-gP P) 4)
	(= (prod-by-synthesis CEBP-pRbp1p2-gP P) 4)
	(association-reaction CEBP pRbp2 CEBP-pRbp2)
	(= (need-for-association CEBP pRbp2 CEBP-pRbp2) 2)
	(= (need-for-association pRbp2 CEBP CEBP-pRbp2) 3)
	(= (prod-by-association CEBP pRbp2 CEBP-pRbp2) 2)
	(association-reaction CEBP-pRbp2 gP CEBP-pRbp2-gP)
	(= (need-for-association CEBP-pRbp2 gP CEBP-pRbp2-gP) 2)
	(= (need-for-association gP CEBP-pRbp2 CEBP-pRbp2-gP) 2)
	(= (prod-by-association CEBP-pRbp2 gP CEBP-pRbp2-gP) 3)
	(synthesis-reaction CEBP-pRbp2-gP P) 
	(= (need-for-synthesis CEBP-pRbp2-gP P) 1)
	(= (prod-by-synthesis CEBP-pRbp2-gP P) 4)
	(catalyzed-association-reaction cycA Skp2p1-Skp1 Skp2p1-Skp1)
	(= (need-for-catalyzed-association cycA Skp2p1-Skp1 Skp2p1-Skp1) 1)
	(= (need-for-catalyzed-association Skp2p1-Skp1 cycA Skp2p1-Skp1) 4)
	(= (prod-by-catalyzed-association cycA Skp2p1-Skp1 Skp2p1-Skp1) 2)
	(catalyzed-association-reaction cycA Skp2p1-Skp1p1 Skp2p1-Skp1p1)
	(= (need-for-catalyzed-association cycA Skp2p1-Skp1p1 Skp2p1-Skp1p1) 1)
	(= (need-for-catalyzed-association Skp2p1-Skp1p1 cycA Skp2p1-Skp1p1) 4)
	(= (prod-by-catalyzed-association cycA Skp2p1-Skp1p1 Skp2p1-Skp1p1) 3)
	(catalyzed-association-reaction cycA Skp2-Skp1 Skp2-Skp1)
	(= (need-for-catalyzed-association cycA Skp2-Skp1 Skp2-Skp1) 3)
	(= (need-for-catalyzed-association Skp2-Skp1 cycA Skp2-Skp1) 3)
	(= (prod-by-catalyzed-association cycA Skp2-Skp1 Skp2-Skp1) 1)
	(catalyzed-association-reaction cycA Skp2-Skp1p1 Skp2-Skp1p1)
	(= (need-for-catalyzed-association cycA Skp2-Skp1p1 Skp2-Skp1p1) 3)
	(= (need-for-catalyzed-association Skp2-Skp1p1 cycA Skp2-Skp1p1) 3)
	(= (prod-by-catalyzed-association cycA Skp2-Skp1p1 Skp2-Skp1p1) 4)
	(catalyzed-association-reaction cycE cdk2p2-cycE cycEp1)
	(= (need-for-catalyzed-association cycE cdk2p2-cycE cycEp1) 2)
	(= (need-for-catalyzed-association cdk2p2-cycE cycE cycEp1) 4)
	(= (prod-by-catalyzed-association cycE cdk2p2-cycE cycEp1) 3)
	(catalyzed-association-reaction cycE cdk2p2-cycEp1 cycEp1)
	(= (need-for-catalyzed-association cycE cdk2p2-cycEp1 cycEp1) 4)
	(= (need-for-catalyzed-association cdk2p2-cycEp1 cycE cycEp1) 2)
	(= (prod-by-catalyzed-association cycE cdk2p2-cycEp1 cycEp1) 4)
	(catalyzed-association-reaction DP12 cdk2p2-cycA DP12p1)
	(= (need-for-catalyzed-association DP12 cdk2p2-cycA DP12p1) 3)
	(= (need-for-catalyzed-association cdk2p2-cycA DP12 DP12p1) 1)
	(= (prod-by-catalyzed-association DP12 cdk2p2-cycA DP12p1) 1)
	(association-reaction E2F1 DP12 E2F1-DP12)
	(= (need-for-association E2F1 DP12 E2F1-DP12) 2)
	(= (need-for-association DP12 E2F1 E2F1-DP12) 1)
	(= (prod-by-association E2F1 DP12 E2F1-DP12) 3)
	(association-reaction E2F2 DP12 E2F2-DP12)
	(= (need-for-association E2F2 DP12 E2F2-DP12) 1)
	(= (need-for-association DP12 E2F2 E2F2-DP12) 2)
	(= (prod-by-association E2F2 DP12 E2F2-DP12) 4)
	(association-reaction E2F3 DP12 E2F3-DP12)
	(= (need-for-association E2F3 DP12 E2F3-DP12) 2)
	(= (need-for-association DP12 E2F3 E2F3-DP12) 1)
	(= (prod-by-association E2F3 DP12 E2F3-DP12) 4)
	(association-reaction E2F4 DP12 E2F4-DP12)
	(= (need-for-association E2F4 DP12 E2F4-DP12) 1)
	(= (need-for-association DP12 E2F4 E2F4-DP12) 1)
	(= (prod-by-association E2F4 DP12 E2F4-DP12) 3)
	(association-reaction E2F5 DP12 E2F5-DP12)
	(= (need-for-association E2F5 DP12 E2F5-DP12) 3)
	(= (need-for-association DP12 E2F5 E2F5-DP12) 1)
	(= (prod-by-association E2F5 DP12 E2F5-DP12) 2)
	(association-reaction E2F6 DP12 E2F6-DP12)
	(= (need-for-association E2F6 DP12 E2F6-DP12) 1)
	(= (need-for-association DP12 E2F6 E2F6-DP12) 4)
	(= (prod-by-association E2F6 DP12 E2F6-DP12) 4)
	(association-reaction HDAC1 p107-E2F4-DP12 HDAC1-p107-E2F4-DP12)
	(= (need-for-association HDAC1 p107-E2F4-DP12 HDAC1-p107-E2F4-DP12) 1)
	(= (need-for-association p107-E2F4-DP12 HDAC1 HDAC1-p107-E2F4-DP12) 2)
	(= (prod-by-association HDAC1 p107-E2F4-DP12 HDAC1-p107-E2F4-DP12) 2)
	(association-reaction HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12)
	(= (need-for-association HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 4)
	(= (need-for-association pRb-E2F13-DP12 HDAC1 HDAC1-pRb-E2F13-DP12) 4)
	(= (prod-by-association HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 1)
	(association-reaction HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12)
	(= (need-for-association HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 2)
	(= (need-for-association pRb-E2F13p1-DP12 HDAC1 HDAC1-pRb-E2F13p1-DP12) 3)
	(= (prod-by-association HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 2)
	(association-reaction HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1)
	(= (need-for-association HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 2)
	(= (need-for-association pRb-E2F13p1-DP12p1 HDAC1 HDAC1-pRb-E2F13p1-DP12p1) 2)
	(= (prod-by-association HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 3)
	(association-reaction HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12)
	(= (need-for-association HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12) 2)
	(= (need-for-association pRb-E2F4-DP12 HDAC1 HDAC1-pRb-E2F4-DP12) 3)
	(= (prod-by-association HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12) 3)
	(association-reaction HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12)
	(= (need-for-association HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12) 4)
	(= (need-for-association pRb-E2F4p1-DP12 HDAC1 HDAC1-pRb-E2F4p1-DP12) 3)
	(= (prod-by-association HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12) 4)
	(synthesis-reaction Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis Jun-c-Fos-gERCC1 ERCC1) 3)
	(= (prod-by-synthesis Jun-c-Fos-gERCC1 ERCC1) 1)
	(association-reaction Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1)
	(= (need-for-association Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1) 4)
	(= (need-for-association gERCC1 Jun-c-Fos Jun-c-Fos-gERCC1) 2)
	(= (prod-by-association Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1) 1)
	(association-reaction Jun c-Fos Jun-c-Fos)
	(= (need-for-association Jun c-Fos Jun-c-Fos) 1)
	(= (need-for-association c-Fos Jun Jun-c-Fos) 1)
	(= (prod-by-association Jun c-Fos Jun-c-Fos) 3)
	(association-reaction m1433 cdc25Cp2 m1433-cdc25Cp2)
	(= (need-for-association m1433 cdc25Cp2 m1433-cdc25Cp2) 1)
	(= (need-for-association cdc25Cp2 m1433 m1433-cdc25Cp2) 2)
	(= (prod-by-association m1433 cdc25Cp2 m1433-cdc25Cp2) 4)
	(association-reaction Mdm2 E2F13-DP12 Mdm2-E2F13-DP12)
	(= (need-for-association Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 4)
	(= (need-for-association E2F13-DP12 Mdm2 Mdm2-E2F13-DP12) 2)
	(= (prod-by-association Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 4)
	(association-reaction Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12)
	(= (need-for-association Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 2)
	(= (need-for-association E2F13p1-DP12 Mdm2 Mdm2-E2F13p1-DP12) 3)
	(= (prod-by-association Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 4)
	(association-reaction Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1)
	(= (need-for-association Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 1)
	(= (need-for-association E2F13p1-DP12p1 Mdm2 Mdm2-E2F13p1-DP12p1) 4)
	(= (prod-by-association Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 1)
	(association-reaction Mdm2 pRb Mdm2-pRb)
	(= (need-for-association Mdm2 pRb Mdm2-pRb) 3)
	(= (need-for-association pRb Mdm2 Mdm2-pRb) 1)
	(= (prod-by-association Mdm2 pRb Mdm2-pRb) 2)
	(association-reaction Mdm2 pRbp1 Mdm2-pRbp1)
	(= (need-for-association Mdm2 pRbp1 Mdm2-pRbp1) 4)
	(= (need-for-association pRbp1 Mdm2 Mdm2-pRbp1) 3)
	(= (prod-by-association Mdm2 pRbp1 Mdm2-pRbp1) 4)
	(association-reaction Mdm2 pRbp1p2 Mdm2-pRbp1p2)
	(= (need-for-association Mdm2 pRbp1p2 Mdm2-pRbp1p2) 3)
	(= (need-for-association pRbp1p2 Mdm2 Mdm2-pRbp1p2) 1)
	(= (prod-by-association Mdm2 pRbp1p2 Mdm2-pRbp1p2) 3)
	(association-reaction Mdm2 pRbp2 Mdm2-pRbp2)
	(= (need-for-association Mdm2 pRbp2 Mdm2-pRbp2) 1)
	(= (need-for-association pRbp2 Mdm2 Mdm2-pRbp2) 1)
	(= (prod-by-association Mdm2 pRbp2 Mdm2-pRbp2) 2)
	(association-reaction p107 E2F4-DP12 p107-E2F4-DP12)
	(= (need-for-association p107 E2F4-DP12 p107-E2F4-DP12) 1)
	(= (need-for-association E2F4-DP12 p107 p107-E2F4-DP12) 4)
	(= (prod-by-association p107 E2F4-DP12 p107-E2F4-DP12) 3)
	(association-reaction p16 cdk46p1 p16-cdk46p1)
	(= (need-for-association p16 cdk46p1 p16-cdk46p1) 2)
	(= (need-for-association cdk46p1 p16 p16-cdk46p1) 4)
	(= (prod-by-association p16 cdk46p1 p16-cdk46p1) 3)
	(association-reaction p16 cdk46p1p2 p16-cdk46p1p2)
	(= (need-for-association p16 cdk46p1p2 p16-cdk46p1p2) 4)
	(= (need-for-association cdk46p1p2 p16 p16-cdk46p1p2) 1)
	(= (prod-by-association p16 cdk46p1p2 p16-cdk46p1p2) 1)
	(association-reaction p16 cdk7 p16-cdk7)
	(= (need-for-association p16 cdk7 p16-cdk7) 3)
	(= (need-for-association cdk7 p16 p16-cdk7) 4)
	(= (prod-by-association p16 cdk7 p16-cdk7) 2)
	(association-reaction p16 cdk7p1 p16-cdk7p1)
	(= (need-for-association p16 cdk7p1 p16-cdk7p1) 3)
	(= (need-for-association cdk7p1 p16 p16-cdk7p1) 1)
	(= (prod-by-association p16 cdk7p1 p16-cdk7p1) 4)
	(association-reaction p21 cdk2-cycA p21-cdk2-cycA)
	(= (need-for-association p21 cdk2-cycA p21-cdk2-cycA) 2)
	(= (need-for-association cdk2-cycA p21 p21-cdk2-cycA) 1)
	(= (prod-by-association p21 cdk2-cycA p21-cdk2-cycA) 3)
	(association-reaction p21 cdk2-cycEp1 p21-cdk2-cycEp1)
	(= (need-for-association p21 cdk2-cycEp1 p21-cdk2-cycEp1) 2)
	(= (need-for-association cdk2-cycEp1 p21 p21-cdk2-cycEp1) 4)
	(= (prod-by-association p21 cdk2-cycEp1 p21-cdk2-cycEp1) 4)
	(association-reaction p21 cdk2-cycE p21-cdk2-cycE)
	(= (need-for-association p21 cdk2-cycE p21-cdk2-cycE) 4)
	(= (need-for-association cdk2-cycE p21 p21-cdk2-cycE) 3)
	(= (prod-by-association p21 cdk2-cycE p21-cdk2-cycE) 2)
	(association-reaction p21 cdk2p1-cycA p21-cdk2p1-cycA)
	(= (need-for-association p21 cdk2p1-cycA p21-cdk2p1-cycA) 3)
	(= (need-for-association cdk2p1-cycA p21 p21-cdk2p1-cycA) 1)
	(= (prod-by-association p21 cdk2p1-cycA p21-cdk2p1-cycA) 3)
	(association-reaction p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1)
	(= (need-for-association p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1) 1)
	(= (need-for-association cdk2p1-cycEp1 p21 p21-cdk2p1-cycEp1) 2)
	(= (prod-by-association p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1) 3)
	(association-reaction p21 cdk2p1-cycE p21-cdk2p1-cycE)
	(= (need-for-association p21 cdk2p1-cycE p21-cdk2p1-cycE) 2)
	(= (need-for-association cdk2p1-cycE p21 p21-cdk2p1-cycE) 2)
	(= (prod-by-association p21 cdk2p1-cycE p21-cdk2p1-cycE) 2)
	(association-reaction p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA)
	(= (need-for-association p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA) 1)
	(= (need-for-association cdk2p1p2-cycA p21 p21-cdk2p1p2-cycA) 3)
	(= (prod-by-association p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA) 2)
	(association-reaction p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1)
	(= (need-for-association p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1) 3)
	(= (need-for-association cdk2p1p2-cycEp1 p21 p21-cdk2p1p2-cycEp1) 3)
	(= (prod-by-association p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1) 2)
	(association-reaction p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE)
	(= (need-for-association p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE) 3)
	(= (need-for-association cdk2p1p2-cycE p21 p21-cdk2p1p2-cycE) 1)
	(= (prod-by-association p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE) 1)
	(association-reaction p21 cdk2p2-cycA p21-cdk2p2-cycA)
	(= (need-for-association p21 cdk2p2-cycA p21-cdk2p2-cycA) 4)
	(= (need-for-association cdk2p2-cycA p21 p21-cdk2p2-cycA) 3)
	(= (prod-by-association p21 cdk2p2-cycA p21-cdk2p2-cycA) 2)
	(association-reaction p21 cdk2p2-cycEp1 p21-cdk2p2-cycEp1)
	(= (need-for-association p21 cdk2p2-cycEp1 p21-cdk2p2-cycEp1) 4)
	(= (need-for-association cdk2p2-cycEp1 p21 p21-cdk2p2-cycEp1) 4)
	(= (prod-by-association p21 cdk2p2-cycEp1 p21-cdk2p2-cycEp1) 2)
	(association-reaction p21 cdk2p2-cycE p21-cdk2p2-cycE)
	(= (need-for-association p21 cdk2p2-cycE p21-cdk2p2-cycE) 2)
	(= (need-for-association cdk2p2-cycE p21 p21-cdk2p2-cycE) 2)
	(= (prod-by-association p21 cdk2p2-cycE p21-cdk2p2-cycE) 1)
	(association-reaction p21 cdk46p1-cycDp1 p21-cdk46p1-cycDp1)
	(= (need-for-association p21 cdk46p1-cycDp1 p21-cdk46p1-cycDp1) 1)
	(= (need-for-association cdk46p1-cycDp1 p21 p21-cdk46p1-cycDp1) 1)
	(= (prod-by-association p21 cdk46p1-cycDp1 p21-cdk46p1-cycDp1) 4)
	(association-reaction p21 cdk46p1-cycD p21-cdk46p1-cycD)
	(= (need-for-association p21 cdk46p1-cycD p21-cdk46p1-cycD) 3)
	(= (need-for-association cdk46p1-cycD p21 p21-cdk46p1-cycD) 3)
	(= (prod-by-association p21 cdk46p1-cycD p21-cdk46p1-cycD) 4)
	(association-reaction p21 cdk46p1p2-cycDp1 p21-cdk46p1p2-cycDp1)
	(= (need-for-association p21 cdk46p1p2-cycDp1 p21-cdk46p1p2-cycDp1) 1)
	(= (need-for-association cdk46p1p2-cycDp1 p21 p21-cdk46p1p2-cycDp1) 3)
	(= (prod-by-association p21 cdk46p1p2-cycDp1 p21-cdk46p1p2-cycDp1) 1)
	(association-reaction p21 cdk46p1p2-cycD p21-cdk46p1p2-cycD)
	(= (need-for-association p21 cdk46p1p2-cycD p21-cdk46p1p2-cycD) 3)
	(= (need-for-association cdk46p1p2-cycD p21 p21-cdk46p1p2-cycD) 1)
	(= (prod-by-association p21 cdk46p1p2-cycD p21-cdk46p1p2-cycD) 3)
	(association-reaction p21 Gadd45 p21-Gadd45)
	(= (need-for-association p21 Gadd45 p21-Gadd45) 4)
	(= (need-for-association Gadd45 p21 p21-Gadd45) 1)
	(= (prod-by-association p21 Gadd45 p21-Gadd45) 1)
	(synthesis-reaction p53 c-Fos) 
	(= (need-for-synthesis p53 c-Fos) 1)
	(= (prod-by-synthesis p53 c-Fos) 3)
	(association-reaction p53 DP12p1 p53-DP12p1)
	(= (need-for-association p53 DP12p1 p53-DP12p1) 3)
	(= (need-for-association DP12p1 p53 p53-DP12p1) 2)
	(= (prod-by-association p53 DP12p1 p53-DP12p1) 2)
	(association-reaction p53 DP12 p53-DP12)
	(= (need-for-association p53 DP12 p53-DP12) 4)
	(= (need-for-association DP12 p53 p53-DP12) 3)
	(= (prod-by-association p53 DP12 p53-DP12) 1)
	(synthesis-reaction p53 Gadd45) 
	(= (need-for-synthesis p53 Gadd45) 2)
	(= (prod-by-synthesis p53 Gadd45) 4)
	(synthesis-reaction p53 Mdm2) 
	(= (need-for-synthesis p53 Mdm2) 4)
	(= (prod-by-synthesis p53 Mdm2) 2)
	(synthesis-reaction p53p1 c-Fos) 
	(= (need-for-synthesis p53p1 c-Fos) 1)
	(= (prod-by-synthesis p53p1 c-Fos) 2)
	(association-reaction p53p1 DP12p1 p53p1-DP12p1)
	(= (need-for-association p53p1 DP12p1 p53p1-DP12p1) 3)
	(= (need-for-association DP12p1 p53p1 p53p1-DP12p1) 2)
	(= (prod-by-association p53p1 DP12p1 p53p1-DP12p1) 2)
	(association-reaction p53p1 DP12 p53p1-DP12)
	(= (need-for-association p53p1 DP12 p53p1-DP12) 3)
	(= (need-for-association DP12 p53p1 p53p1-DP12) 1)
	(= (prod-by-association p53p1 DP12 p53p1-DP12) 4)
	(synthesis-reaction p53p1 Gadd45) 
	(= (need-for-synthesis p53p1 Gadd45) 1)
	(= (prod-by-synthesis p53p1 Gadd45) 4)
	(synthesis-reaction p53p1 Mdm2) 
	(= (need-for-synthesis p53p1 Mdm2) 4)
	(= (prod-by-synthesis p53p1 Mdm2) 3)
	(synthesis-reaction p53p1 p21) 
	(= (need-for-synthesis p53p1 p21) 1)
	(= (prod-by-synthesis p53p1 p21) 2)
	(synthesis-reaction p53 p21) 
	(= (need-for-synthesis p53 p21) 3)
	(= (prod-by-synthesis p53 p21) 3)
	(catalyzed-association-reaction p68 cdk2p2-cycA p68p2)
	(= (need-for-catalyzed-association p68 cdk2p2-cycA p68p2) 2)
	(= (need-for-catalyzed-association cdk2p2-cycA p68 p68p2) 3)
	(= (prod-by-catalyzed-association p68 cdk2p2-cycA p68p2) 3)
	(catalyzed-association-reaction p68 cdk2p2-cycEp1 p68p1)
	(= (need-for-catalyzed-association p68 cdk2p2-cycEp1 p68p1) 2)
	(= (need-for-catalyzed-association cdk2p2-cycEp1 p68 p68p1) 2)
	(= (prod-by-catalyzed-association p68 cdk2p2-cycEp1 p68p1) 2)
	(catalyzed-association-reaction p68 cdk2p2-cycE p68p1)
	(= (need-for-catalyzed-association p68 cdk2p2-cycE p68p1) 4)
	(= (need-for-catalyzed-association cdk2p2-cycE p68 p68p1) 3)
	(= (prod-by-catalyzed-association p68 cdk2p2-cycE p68p1) 1)
	(catalyzed-association-reaction p68p1 cdk2p2-cycA p68p1p2)
	(= (need-for-catalyzed-association p68p1 cdk2p2-cycA p68p1p2) 2)
	(= (need-for-catalyzed-association cdk2p2-cycA p68p1 p68p1p2) 3)
	(= (prod-by-catalyzed-association p68p1 cdk2p2-cycA p68p1p2) 2)
	(catalyzed-association-reaction p68p2 cdk2p2-cycEp1 p68p1p2)
	(= (need-for-catalyzed-association p68p2 cdk2p2-cycEp1 p68p1p2) 1)
	(= (need-for-catalyzed-association cdk2p2-cycEp1 p68p2 p68p1p2) 3)
	(= (prod-by-catalyzed-association p68p2 cdk2p2-cycEp1 p68p1p2) 3)
	(catalyzed-association-reaction p68p2 cdk2p2-cycE p68p1p2)
	(= (need-for-catalyzed-association p68p2 cdk2p2-cycE p68p1p2) 1)
	(= (need-for-catalyzed-association cdk2p2-cycE p68p2 p68p1p2) 4)
	(= (prod-by-catalyzed-association p68p2 cdk2p2-cycE p68p1p2) 1)
	(catalyzed-association-reaction pRb cdk46p3-cycDp1 pRbp1)
	(= (need-for-catalyzed-association pRb cdk46p3-cycDp1 pRbp1) 2)
	(= (need-for-catalyzed-association cdk46p3-cycDp1 pRb pRbp1) 1)
	(= (prod-by-catalyzed-association pRb cdk46p3-cycDp1 pRbp1) 3)
	(catalyzed-association-reaction pRb cdk46p3-cycD pRbp1)
	(= (need-for-catalyzed-association pRb cdk46p3-cycD pRbp1) 2)
	(= (need-for-catalyzed-association cdk46p3-cycD pRb pRbp1) 1)
	(= (prod-by-catalyzed-association pRb cdk46p3-cycD pRbp1) 3)
	(association-reaction pRb E2F13-DP12 pRb-E2F13-DP12)
	(= (need-for-association pRb E2F13-DP12 pRb-E2F13-DP12) 2)
	(= (need-for-association E2F13-DP12 pRb pRb-E2F13-DP12) 4)
	(= (prod-by-association pRb E2F13-DP12 pRb-E2F13-DP12) 2)
	(association-reaction pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1)
	(= (need-for-association pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 2)
	(= (need-for-association E2F13p1-DP12p1 pRb pRb-E2F13p1-DP12p1) 2)
	(= (prod-by-association pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 4)
	(association-reaction pRb E2F13p1-DP12 pRb-E2F13p1-DP12)
	(= (need-for-association pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 4)
	(= (need-for-association E2F13p1-DP12 pRb pRb-E2F13p1-DP12) 3)
	(= (prod-by-association pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 3)
	(association-reaction pRb E2F4-DP12 pRb-E2F4-DP12)
	(= (need-for-association pRb E2F4-DP12 pRb-E2F4-DP12) 2)
	(= (need-for-association E2F4-DP12 pRb pRb-E2F4-DP12) 4)
	(= (prod-by-association pRb E2F4-DP12 pRb-E2F4-DP12) 4)
	(synthesis-reaction pRb-Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis pRb-Jun-c-Fos-gERCC1 ERCC1) 3)
	(= (prod-by-synthesis pRb-Jun-c-Fos-gERCC1 ERCC1) 3)
	(association-reaction pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1)
	(= (need-for-association pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1) 2)
	(= (need-for-association gERCC1 pRb-Jun-c-Fos pRb-Jun-c-Fos-gERCC1) 3)
	(= (prod-by-association pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1) 4)
	(association-reaction pRb-Jun c-Fos pRb-Jun-c-Fos)
	(= (need-for-association pRb-Jun c-Fos pRb-Jun-c-Fos) 4)
	(= (need-for-association c-Fos pRb-Jun pRb-Jun-c-Fos) 1)
	(= (prod-by-association pRb-Jun c-Fos pRb-Jun-c-Fos) 4)
	(association-reaction pRb Jun pRb-Jun)
	(= (need-for-association pRb Jun pRb-Jun) 2)
	(= (need-for-association Jun pRb pRb-Jun) 3)
	(= (prod-by-association pRb Jun pRb-Jun) 1)
	(catalyzed-association-reaction pRbp1 cdk2p2-cycEp1 pRbp1p2)
	(= (need-for-catalyzed-association pRbp1 cdk2p2-cycEp1 pRbp1p2) 1)
	(= (need-for-catalyzed-association cdk2p2-cycEp1 pRbp1 pRbp1p2) 4)
	(= (prod-by-catalyzed-association pRbp1 cdk2p2-cycEp1 pRbp1p2) 2)
	(catalyzed-association-reaction pRbp1 cdk2p2-cycE pRbp1p2)
	(= (need-for-catalyzed-association pRbp1 cdk2p2-cycE pRbp1p2) 2)
	(= (need-for-catalyzed-association cdk2p2-cycE pRbp1 pRbp1p2) 2)
	(= (prod-by-catalyzed-association pRbp1 cdk2p2-cycE pRbp1p2) 4)
	(association-reaction pRbp1 E2F13-DP12 pRbp1-E2F13-DP12)
	(= (need-for-association pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 2)
	(= (need-for-association E2F13-DP12 pRbp1 pRbp1-E2F13-DP12) 1)
	(= (prod-by-association pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 1)
	(association-reaction pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1)
	(= (need-for-association pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 1)
	(= (need-for-association E2F13p1-DP12p1 pRbp1 pRbp1-E2F13p1-DP12p1) 2)
	(= (prod-by-association pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 2)
	(association-reaction pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12)
	(= (need-for-association pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 2)
	(= (need-for-association E2F13p1-DP12 pRbp1 pRbp1-E2F13p1-DP12) 1)
	(= (prod-by-association pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 1)
	(association-reaction pRbp1 E2F4-DP12 pRbp1-E2F4-DP12)
	(= (need-for-association pRbp1 E2F4-DP12 pRbp1-E2F4-DP12) 4)
	(= (need-for-association E2F4-DP12 pRbp1 pRbp1-E2F4-DP12) 3)
	(= (prod-by-association pRbp1 E2F4-DP12 pRbp1-E2F4-DP12) 2)
	(synthesis-reaction pRbp1-Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis pRbp1-Jun-c-Fos-gERCC1 ERCC1) 4)
	(= (prod-by-synthesis pRbp1-Jun-c-Fos-gERCC1 ERCC1) 2)
	(association-reaction pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1)
	(= (need-for-association pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1) 1)
	(= (need-for-association gERCC1 pRbp1-Jun-c-Fos pRbp1-Jun-c-Fos-gERCC1) 2)
	(= (prod-by-association pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1) 3)
	(association-reaction pRbp1-Jun c-Fos pRbp1-Jun-c-Fos)
	(= (need-for-association pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 3)
	(= (need-for-association c-Fos pRbp1-Jun pRbp1-Jun-c-Fos) 2)
	(= (prod-by-association pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 3)
	(association-reaction pRbp1 Jun pRbp1-Jun)
	(= (need-for-association pRbp1 Jun pRbp1-Jun) 3)
	(= (need-for-association Jun pRbp1 pRbp1-Jun) 1)
	(= (prod-by-association pRbp1 Jun pRbp1-Jun) 4)
	(synthesis-reaction pRbp1p2-Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis pRbp1p2-Jun-c-Fos-gERCC1 ERCC1) 2)
	(= (prod-by-synthesis pRbp1p2-Jun-c-Fos-gERCC1 ERCC1) 1)
	(association-reaction pRbp1p2-Jun-c-Fos gERCC1 pRbp1p2-Jun-c-Fos-gERCC1)
	(= (need-for-association pRbp1p2-Jun-c-Fos gERCC1 pRbp1p2-Jun-c-Fos-gERCC1) 1)
	(= (need-for-association gERCC1 pRbp1p2-Jun-c-Fos pRbp1p2-Jun-c-Fos-gERCC1) 1)
	(= (prod-by-association pRbp1p2-Jun-c-Fos gERCC1 pRbp1p2-Jun-c-Fos-gERCC1) 3)
	(association-reaction pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos)
	(= (need-for-association pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos) 2)
	(= (need-for-association c-Fos pRbp1p2-Jun pRbp1p2-Jun-c-Fos) 2)
	(= (prod-by-association pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos) 2)
	(association-reaction pRbp1p2 Jun pRbp1p2-Jun)
	(= (need-for-association pRbp1p2 Jun pRbp1p2-Jun) 3)
	(= (need-for-association Jun pRbp1p2 pRbp1p2-Jun) 2)
	(= (prod-by-association pRbp1p2 Jun pRbp1p2-Jun) 2)
	(catalyzed-association-reaction pRbp2 cdk46p3-cycDp1 pRbp1p2)
	(= (need-for-catalyzed-association pRbp2 cdk46p3-cycDp1 pRbp1p2) 3)
	(= (need-for-catalyzed-association cdk46p3-cycDp1 pRbp2 pRbp1p2) 3)
	(= (prod-by-catalyzed-association pRbp2 cdk46p3-cycDp1 pRbp1p2) 3)
	(catalyzed-association-reaction pRbp2 cdk46p3-cycD pRbp1p2)
	(= (need-for-catalyzed-association pRbp2 cdk46p3-cycD pRbp1p2) 1)
	(= (need-for-catalyzed-association cdk46p3-cycD pRbp2 pRbp1p2) 4)
	(= (prod-by-catalyzed-association pRbp2 cdk46p3-cycD pRbp1p2) 3)
	(synthesis-reaction pRbp2-Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis pRbp2-Jun-c-Fos-gERCC1 ERCC1) 4)
	(= (prod-by-synthesis pRbp2-Jun-c-Fos-gERCC1 ERCC1) 2)
	(association-reaction pRbp2-Jun-c-Fos gERCC1 pRbp2-Jun-c-Fos-gERCC1)
	(= (need-for-association pRbp2-Jun-c-Fos gERCC1 pRbp2-Jun-c-Fos-gERCC1) 4)
	(= (need-for-association gERCC1 pRbp2-Jun-c-Fos pRbp2-Jun-c-Fos-gERCC1) 3)
	(= (prod-by-association pRbp2-Jun-c-Fos gERCC1 pRbp2-Jun-c-Fos-gERCC1) 4)
	(association-reaction pRbp2-Jun c-Fos pRbp2-Jun-c-Fos)
	(= (need-for-association pRbp2-Jun c-Fos pRbp2-Jun-c-Fos) 4)
	(= (need-for-association c-Fos pRbp2-Jun pRbp2-Jun-c-Fos) 1)
	(= (prod-by-association pRbp2-Jun c-Fos pRbp2-Jun-c-Fos) 2)
	(association-reaction pRbp2 Jun pRbp2-Jun)
	(= (need-for-association pRbp2 Jun pRbp2-Jun) 3)
	(= (need-for-association Jun pRbp2 pRbp2-Jun) 2)
	(= (prod-by-association pRbp2 Jun pRbp2-Jun) 4)
	(association-reaction RPA cycA RPA-cycA)
	(= (need-for-association RPA cycA RPA-cycA) 1)
	(= (need-for-association cycA RPA RPA-cycA) 2)
	(= (prod-by-association RPA cycA RPA-cycA) 4)
	(catalyzed-association-reaction Skp1 cdk2p2-cycA Skp1p1)
	(= (need-for-catalyzed-association Skp1 cdk2p2-cycA Skp1p1) 2)
	(= (need-for-catalyzed-association cdk2p2-cycA Skp1 Skp1p1) 3)
	(= (prod-by-catalyzed-association Skp1 cdk2p2-cycA Skp1p1) 4)
	(association-reaction Skp2 cdk2-cycA Skp2-cdk2-cycA)
	(= (need-for-association Skp2 cdk2-cycA Skp2-cdk2-cycA) 2)
	(= (need-for-association cdk2-cycA Skp2 Skp2-cdk2-cycA) 1)
	(= (prod-by-association Skp2 cdk2-cycA Skp2-cdk2-cycA) 1)
	(association-reaction Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA)
	(= (need-for-association Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA) 4)
	(= (need-for-association cdk2p1-cycA Skp2 Skp2-cdk2p1-cycA) 2)
	(= (prod-by-association Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA) 3)
	(association-reaction Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA)
	(= (need-for-association Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA) 1)
	(= (need-for-association cdk2p1p2-cycA Skp2 Skp2-cdk2p1p2-cycA) 3)
	(= (prod-by-association Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA) 1)
	(association-reaction Skp2 cdk2p2-cycA Skp2-cdk2p2-cycA)
	(= (need-for-association Skp2 cdk2p2-cycA Skp2-cdk2p2-cycA) 4)
	(= (need-for-association cdk2p2-cycA Skp2 Skp2-cdk2p2-cycA) 1)
	(= (prod-by-association Skp2 cdk2p2-cycA Skp2-cdk2p2-cycA) 1)
	(catalyzed-association-reaction Skp2 cdk2p2-cycA Skp2p1)
	(= (need-for-catalyzed-association Skp2 cdk2p2-cycA Skp2p1) 3)
	(= (need-for-catalyzed-association cdk2p2-cycA Skp2 Skp2p1) 3)
	(= (prod-by-catalyzed-association Skp2 cdk2p2-cycA Skp2p1) 1)
	(association-reaction Skp2p1 Skp1p1 Skp2p1-Skp1p1)
	(= (need-for-association Skp2p1 Skp1p1 Skp2p1-Skp1p1) 4)
	(= (need-for-association Skp1p1 Skp2p1 Skp2p1-Skp1p1) 2)
	(= (prod-by-association Skp2p1 Skp1p1 Skp2p1-Skp1p1) 3)
	(association-reaction Skp2p1 Skp1 Skp2p1-Skp1)
	(= (need-for-association Skp2p1 Skp1 Skp2p1-Skp1) 3)
	(= (need-for-association Skp1 Skp2p1 Skp2p1-Skp1) 2)
	(= (prod-by-association Skp2p1 Skp1 Skp2p1-Skp1) 3)
	(association-reaction Skp2-Skp1 cdk2-cycA Skp2-Skp1-cdk2-cycA)
	(= (need-for-association Skp2-Skp1 cdk2-cycA Skp2-Skp1-cdk2-cycA) 1)
	(= (need-for-association cdk2-cycA Skp2-Skp1 Skp2-Skp1-cdk2-cycA) 4)
	(= (prod-by-association Skp2-Skp1 cdk2-cycA Skp2-Skp1-cdk2-cycA) 4)
	(association-reaction Skp2-Skp1 cdk2p1-cycA Skp2-Skp1-cdk2p1-cycA)
	(= (need-for-association Skp2-Skp1 cdk2p1-cycA Skp2-Skp1-cdk2p1-cycA) 4)
	(= (need-for-association cdk2p1-cycA Skp2-Skp1 Skp2-Skp1-cdk2p1-cycA) 4)
	(= (prod-by-association Skp2-Skp1 cdk2p1-cycA Skp2-Skp1-cdk2p1-cycA) 2)
	(association-reaction Skp2-Skp1 cdk2p1p2-cycA Skp2-Skp1-cdk2p1p2-cycA)
	(= (need-for-association Skp2-Skp1 cdk2p1p2-cycA Skp2-Skp1-cdk2p1p2-cycA) 3)
	(= (need-for-association cdk2p1p2-cycA Skp2-Skp1 Skp2-Skp1-cdk2p1p2-cycA) 2)
	(= (prod-by-association Skp2-Skp1 cdk2p1p2-cycA Skp2-Skp1-cdk2p1p2-cycA) 4)
	(association-reaction Skp2-Skp1 cdk2p2-cycA Skp2-Skp1-cdk2p2-cycA)
	(= (need-for-association Skp2-Skp1 cdk2p2-cycA Skp2-Skp1-cdk2p2-cycA) 2)
	(= (need-for-association cdk2p2-cycA Skp2-Skp1 Skp2-Skp1-cdk2p2-cycA) 3)
	(= (prod-by-association Skp2-Skp1 cdk2p2-cycA Skp2-Skp1-cdk2p2-cycA) 4)
	(association-reaction Skp2-Skp1p1 cdk2-cycA Skp2-Skp1p1-cdk2-cycA)
	(= (need-for-association Skp2-Skp1p1 cdk2-cycA Skp2-Skp1p1-cdk2-cycA) 2)
	(= (need-for-association cdk2-cycA Skp2-Skp1p1 Skp2-Skp1p1-cdk2-cycA) 2)
	(= (prod-by-association Skp2-Skp1p1 cdk2-cycA Skp2-Skp1p1-cdk2-cycA) 1)
	(association-reaction Skp2-Skp1p1 cdk2p1-cycA Skp2-Skp1p1-cdk2p1-cycA)
	(= (need-for-association Skp2-Skp1p1 cdk2p1-cycA Skp2-Skp1p1-cdk2p1-cycA) 4)
	(= (need-for-association cdk2p1-cycA Skp2-Skp1p1 Skp2-Skp1p1-cdk2p1-cycA) 3)
	(= (prod-by-association Skp2-Skp1p1 cdk2p1-cycA Skp2-Skp1p1-cdk2p1-cycA) 3)
	(association-reaction Skp2-Skp1p1 cdk2p1p2-cycA Skp2-Skp1p1-cdk2p1p2-cycA)
	(= (need-for-association Skp2-Skp1p1 cdk2p1p2-cycA Skp2-Skp1p1-cdk2p1p2-cycA) 1)
	(= (need-for-association cdk2p1p2-cycA Skp2-Skp1p1 Skp2-Skp1p1-cdk2p1p2-cycA) 2)
	(= (prod-by-association Skp2-Skp1p1 cdk2p1p2-cycA Skp2-Skp1p1-cdk2p1p2-cycA) 3)
	(association-reaction Skp2-Skp1p1 cdk2p2-cycA Skp2-Skp1p1-cdk2p2-cycA)
	(= (need-for-association Skp2-Skp1p1 cdk2p2-cycA Skp2-Skp1p1-cdk2p2-cycA) 1)
	(= (need-for-association cdk2p2-cycA Skp2-Skp1p1 Skp2-Skp1p1-cdk2p2-cycA) 4)
	(= (prod-by-association Skp2-Skp1p1 cdk2p2-cycA Skp2-Skp1p1-cdk2p2-cycA) 1)
	(association-reaction Skp2 Skp1p1 Skp2-Skp1p1)
	(= (need-for-association Skp2 Skp1p1 Skp2-Skp1p1) 1)
	(= (need-for-association Skp1p1 Skp2 Skp2-Skp1p1) 3)
	(= (prod-by-association Skp2 Skp1p1 Skp2-Skp1p1) 2)
	(association-reaction Skp2 Skp1 Skp2-Skp1)
	(= (need-for-association Skp2 Skp1 Skp2-Skp1) 4)
	(= (need-for-association Skp1 Skp2 Skp2-Skp1) 2)
	(= (prod-by-association Skp2 Skp1 Skp2-Skp1) 3)
	(synthesis-reaction SP1-gP c-Myc) 
	(= (need-for-synthesis SP1-gP c-Myc) 2)
	(= (prod-by-synthesis SP1-gP c-Myc) 2)
	(synthesis-reaction SP1-gP cycA) 
	(= (need-for-synthesis SP1-gP cycA) 2)
	(= (prod-by-synthesis SP1-gP cycA) 2)
	(synthesis-reaction SP1-gP cycD) 
	(= (need-for-synthesis SP1-gP cycD) 1)
	(= (prod-by-synthesis SP1-gP cycD) 2)
	(synthesis-reaction SP1-gP cycDp1) 
	(= (need-for-synthesis SP1-gP cycDp1) 3)
	(= (prod-by-synthesis SP1-gP cycDp1) 4)
	(synthesis-reaction SP1-gP cycE) 
	(= (need-for-synthesis SP1-gP cycE) 3)
	(= (prod-by-synthesis SP1-gP cycE) 2)
	(synthesis-reaction SP1-gP cycEp1) 
	(= (need-for-synthesis SP1-gP cycEp1) 1)
	(= (prod-by-synthesis SP1-gP cycEp1) 1)
	(synthesis-reaction SP1-gP p107) 
	(= (need-for-synthesis SP1-gP p107) 1)
	(= (prod-by-synthesis SP1-gP p107) 3)
	(synthesis-reaction SP1-gP p107p1) 
	(= (need-for-synthesis SP1-gP p107p1) 3)
	(= (prod-by-synthesis SP1-gP p107p1) 1)
	(synthesis-reaction SP1-gP p19ARF) 
	(= (need-for-synthesis SP1-gP p19ARF) 2)
	(= (prod-by-synthesis SP1-gP p19ARF) 1)
	(synthesis-reaction SP1-gP pol) 
	(= (need-for-synthesis SP1-gP pol) 3)
	(= (prod-by-synthesis SP1-gP pol) 2)
	(association-reaction SP1 gP SP1-gP)
	(= (need-for-association SP1 gP SP1-gP) 2)
	(= (need-for-association gP SP1 SP1-gP) 1)
	(= (prod-by-association SP1 gP SP1-gP) 3)
	(association-reaction SP1-p107 gP SP1-p107-gP)
	(= (need-for-association SP1-p107 gP SP1-p107-gP) 1)
	(= (need-for-association gP SP1-p107 SP1-p107-gP) 1)
	(= (prod-by-association SP1-p107 gP SP1-p107-gP) 3)
	(association-reaction SP1-p107p1 gP SP1-p107p1-gP)
	(= (need-for-association SP1-p107p1 gP SP1-p107p1-gP) 3)
	(= (need-for-association gP SP1-p107p1 SP1-p107p1-gP) 2)
	(= (prod-by-association SP1-p107p1 gP SP1-p107p1-gP) 2)
	(association-reaction SP1 p107p1 SP1-p107p1)
	(= (need-for-association SP1 p107p1 SP1-p107p1) 4)
	(= (need-for-association p107p1 SP1 SP1-p107p1) 1)
	(= (prod-by-association SP1 p107p1 SP1-p107p1) 4)
	(association-reaction SP1 p107 SP1-p107)
	(= (need-for-association SP1 p107 SP1-p107) 1)
	(= (need-for-association p107 SP1 SP1-p107) 2)
	(= (prod-by-association SP1 p107 SP1-p107) 1)
	(= (num-subs) 0)
	(= (duration-catalyzed-association-reaction cdc25C C-TAK1 cdc25Cp2) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdk7-cycH cdk1p1p2p3) 1.9)
	(= (duration-association-reaction cdk1p1p2 cks1 cdk1p1p2-cks1) 1.1)
	(= (duration-association-reaction cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 0.9)
	(= (duration-association-reaction cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 1.0)
	(= (duration-association-reaction cdk1p1p2p3 cycA cdk1p1p2p3-cycA) 1.1)
	(= (duration-association-reaction cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 1.1)
	(= (duration-association-reaction cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 1.1)
	(= (duration-catalyzed-association-reaction cdk2 cdk7-cycH cdk2p2) 1.9)
	(= (duration-association-reaction cdk2 cks1 cdk2-cks1) 0.9)
	(= (duration-association-reaction cdk2 cycA cdk2-cycA) 1.0)
	(= (duration-catalyzed-association-reaction cdk2-cycA cdk7-cycH cdk2p2-cycA) 1.9)
	(= (duration-catalyzed-association-reaction cdk2-cycA Wee1 cdk2p1-cycA) 1.9)
	(= (duration-catalyzed-association-reaction cdk2-cycB Wee1 cdk2p1-cycB) 1.6)
	(= (duration-association-reaction cdk2 cycE cdk2-cycE) 0.9)
	(= (duration-catalyzed-association-reaction cdk2-cycE cdk7-cycH cdk2p2-cycE) 1.8)
	(= (duration-association-reaction cdk2 cycEp1 cdk2-cycEp1) 0.9)
	(= (duration-catalyzed-association-reaction cdk2-cycEp1 cdk7-cycH cdk2p2-cycEp1) 1.7)
	(= (duration-catalyzed-association-reaction cdk2p1 cdk7-cycH cdk2p1p2) 1.8)
	(= (duration-association-reaction cdk2p1 cks1 cdk2p1-cks1) 1.1)
	(= (duration-association-reaction cdk2p1 cycA cdk2p1-cycA) 0.9)
	(= (duration-catalyzed-association-reaction cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA) 1.6)
	(= (duration-association-reaction cdk2p1 cycE cdk2p1-cycE) 0.8)
	(= (duration-catalyzed-association-reaction cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE) 2.3)
	(= (duration-association-reaction cdk2p1 cycEp1 cdk2p1-cycEp1) 0.9)
	(= (duration-catalyzed-association-reaction cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1) 2.2)
	(= (duration-association-reaction cdk2p1p2 cks1 cdk2p1p2-cks1) 0.8)
	(= (duration-association-reaction cdk2p1p2 cycA cdk2p1p2-cycA) 1.1)
	(= (duration-association-reaction cdk2p1p2 cycE cdk2p1p2-cycE) 0.9)
	(= (duration-association-reaction cdk2p1p2 cycEp1 cdk2p1p2-cycEp1) 0.9)
	(= (duration-association-reaction cdk2p2 cks1 cdk2p2-cks1) 1.0)
	(= (duration-association-reaction cdk2p2 cycA cdk2p2-cycA) 1.1)
	(= (duration-catalyzed-association-reaction cdk2p2-cycA Wee1 cdk2p1p2-cycA) 1.9)
	(= (duration-association-reaction cdk2p2 cycE cdk2p2-cycE) 0.9)
	(= (duration-association-reaction cdk2p2 cycEp1 cdk2p2-cycEp1) 1.0)
	(= (duration-catalyzed-association-reaction cdk46p1 cdk7-cycH cdk46p1p2) 2.2)
	(= (duration-association-reaction cdk46p1 cycD cdk46p1-cycD) 0.9)
	(= (duration-catalyzed-association-reaction cdk46p1-cycD cdk7-cycH cdk46p1p2-cycD) 2.2)
	(= (duration-association-reaction cdk46p1 cycDp1 cdk46p1-cycDp1) 0.9)
	(= (duration-catalyzed-association-reaction cdk46p1-cycDp1 cdk7-cycH cdk46p1p2-cycDp1) 1.7)
	(= (duration-association-reaction cdk46p1p2 cycD cdk46p1p2-cycD) 0.9)
	(= (duration-association-reaction cdk46p1p2 cycDp1 cdk46p1p2-cycDp1) 1.0)
	(= (duration-catalyzed-association-reaction cdk7 cdk7-cycH cdk7p1) 2.0)
	(= (duration-association-reaction cdk7 cycH cdk7-cycH) 0.8)
	(= (duration-catalyzed-association-reaction cdk7-cycH cdk7-cycH cdk7p1-cycH) 2.1)
	(= (duration-association-reaction cdk7p1 cycH cdk7p1-cycH) 0.9)
	(= (duration-association-reaction CEBP gP CEBP-gP) 0.9)
	(= (duration-synthesis-reaction CEBP-gP P) 3.9)
	(= (duration-association-reaction CEBP pRb CEBP-pRb) 1.1)
	(= (duration-association-reaction CEBP-pRb gP CEBP-pRb-gP) 1.0)
	(= (duration-synthesis-reaction CEBP-pRb-gP P) 3.6)
	(= (duration-association-reaction CEBP pRbp1 CEBP-pRbp1) 0.9)
	(= (duration-association-reaction CEBP-pRbp1 gP CEBP-pRbp1-gP) 0.8)
	(= (duration-synthesis-reaction CEBP-pRbp1-gP P) 4.5)
	(= (duration-association-reaction CEBP pRbp1p2 CEBP-pRbp1p2) 1.0)
	(= (duration-association-reaction CEBP-pRbp1p2 gP CEBP-pRbp1p2-gP) 1.1)
	(= (duration-synthesis-reaction CEBP-pRbp1p2-gP P) 3.6)
	(= (duration-association-reaction CEBP pRbp2 CEBP-pRbp2) 1.0)
	(= (duration-association-reaction CEBP-pRbp2 gP CEBP-pRbp2-gP) 1.0)
	(= (duration-synthesis-reaction CEBP-pRbp2-gP P) 3.8)
	(= (duration-catalyzed-association-reaction cycA Skp2p1-Skp1 Skp2p1-Skp1) 1.9)
	(= (duration-catalyzed-association-reaction cycA Skp2p1-Skp1p1 Skp2p1-Skp1p1) 1.9)
	(= (duration-catalyzed-association-reaction cycA Skp2-Skp1 Skp2-Skp1) 2.1)
	(= (duration-catalyzed-association-reaction cycA Skp2-Skp1p1 Skp2-Skp1p1) 2.2)
	(= (duration-catalyzed-association-reaction cycE cdk2p2-cycE cycEp1) 2.1)
	(= (duration-catalyzed-association-reaction cycE cdk2p2-cycEp1 cycEp1) 1.8)
	(= (duration-catalyzed-association-reaction DP12 cdk2p2-cycA DP12p1) 1.8)
	(= (duration-association-reaction E2F1 DP12 E2F1-DP12) 1.0)
	(= (duration-association-reaction E2F2 DP12 E2F2-DP12) 1.0)
	(= (duration-association-reaction E2F3 DP12 E2F3-DP12) 0.9)
	(= (duration-association-reaction E2F4 DP12 E2F4-DP12) 0.8)
	(= (duration-association-reaction E2F5 DP12 E2F5-DP12) 1.1)
	(= (duration-association-reaction E2F6 DP12 E2F6-DP12) 0.8)
	(= (duration-association-reaction HDAC1 p107-E2F4-DP12 HDAC1-p107-E2F4-DP12) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 1.0)
	(= (duration-association-reaction HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12) 1.0)
	(= (duration-association-reaction HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12) 1.0)
	(= (duration-synthesis-reaction Jun-c-Fos-gERCC1 ERCC1) 4.0)
	(= (duration-association-reaction Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1) 1.0)
	(= (duration-association-reaction Jun c-Fos Jun-c-Fos) 1.0)
	(= (duration-association-reaction m1433 cdc25Cp2 m1433-cdc25Cp2) 0.9)
	(= (duration-association-reaction Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 0.9)
	(= (duration-association-reaction Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 1.1)
	(= (duration-association-reaction Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 1.1)
	(= (duration-association-reaction Mdm2 pRb Mdm2-pRb) 1.1)
	(= (duration-association-reaction Mdm2 pRbp1 Mdm2-pRbp1) 0.9)
	(= (duration-association-reaction Mdm2 pRbp1p2 Mdm2-pRbp1p2) 1.1)
	(= (duration-association-reaction Mdm2 pRbp2 Mdm2-pRbp2) 1.1)
	(= (duration-association-reaction p107 E2F4-DP12 p107-E2F4-DP12) 0.8)
	(= (duration-association-reaction p16 cdk46p1 p16-cdk46p1) 0.9)
	(= (duration-association-reaction p16 cdk46p1p2 p16-cdk46p1p2) 0.9)
	(= (duration-association-reaction p16 cdk7 p16-cdk7) 1.1)
	(= (duration-association-reaction p16 cdk7p1 p16-cdk7p1) 0.9)
	(= (duration-association-reaction p21 cdk2-cycA p21-cdk2-cycA) 1.0)
	(= (duration-association-reaction p21 cdk2-cycEp1 p21-cdk2-cycEp1) 1.0)
	(= (duration-association-reaction p21 cdk2-cycE p21-cdk2-cycE) 1.0)
	(= (duration-association-reaction p21 cdk2p1-cycA p21-cdk2p1-cycA) 0.9)
	(= (duration-association-reaction p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1) 0.8)
	(= (duration-association-reaction p21 cdk2p1-cycE p21-cdk2p1-cycE) 0.9)
	(= (duration-association-reaction p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA) 1.0)
	(= (duration-association-reaction p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1) 0.9)
	(= (duration-association-reaction p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE) 1.1)
	(= (duration-association-reaction p21 cdk2p2-cycA p21-cdk2p2-cycA) 1.0)
	(= (duration-association-reaction p21 cdk2p2-cycEp1 p21-cdk2p2-cycEp1) 1.1)
	(= (duration-association-reaction p21 cdk2p2-cycE p21-cdk2p2-cycE) 0.8)
	(= (duration-association-reaction p21 cdk46p1-cycDp1 p21-cdk46p1-cycDp1) 1.1)
	(= (duration-association-reaction p21 cdk46p1-cycD p21-cdk46p1-cycD) 1.1)
	(= (duration-association-reaction p21 cdk46p1p2-cycDp1 p21-cdk46p1p2-cycDp1) 0.9)
	(= (duration-association-reaction p21 cdk46p1p2-cycD p21-cdk46p1p2-cycD) 1.1)
	(= (duration-association-reaction p21 Gadd45 p21-Gadd45) 0.8)
	(= (duration-synthesis-reaction p53 c-Fos) 4.2)
	(= (duration-association-reaction p53 DP12p1 p53-DP12p1) 1.0)
	(= (duration-association-reaction p53 DP12 p53-DP12) 0.9)
	(= (duration-synthesis-reaction p53 Gadd45) 4.0)
	(= (duration-synthesis-reaction p53 Mdm2) 3.6)
	(= (duration-synthesis-reaction p53p1 c-Fos) 4.2)
	(= (duration-association-reaction p53p1 DP12p1 p53p1-DP12p1) 0.9)
	(= (duration-association-reaction p53p1 DP12 p53p1-DP12) 1.0)
	(= (duration-synthesis-reaction p53p1 Gadd45) 4.0)
	(= (duration-synthesis-reaction p53p1 Mdm2) 3.5)
	(= (duration-synthesis-reaction p53p1 p21) 3.2)
	(= (duration-synthesis-reaction p53 p21) 3.7)
	(= (duration-catalyzed-association-reaction p68 cdk2p2-cycA p68p2) 2.3)
	(= (duration-catalyzed-association-reaction p68 cdk2p2-cycEp1 p68p1) 1.7)
	(= (duration-catalyzed-association-reaction p68 cdk2p2-cycE p68p1) 2.2)
	(= (duration-catalyzed-association-reaction p68p1 cdk2p2-cycA p68p1p2) 2.2)
	(= (duration-catalyzed-association-reaction p68p2 cdk2p2-cycEp1 p68p1p2) 1.7)
	(= (duration-catalyzed-association-reaction p68p2 cdk2p2-cycE p68p1p2) 1.7)
	(= (duration-catalyzed-association-reaction pRb cdk46p3-cycDp1 pRbp1) 1.6)
	(= (duration-catalyzed-association-reaction pRb cdk46p3-cycD pRbp1) 1.9)
	(= (duration-association-reaction pRb E2F13-DP12 pRb-E2F13-DP12) 0.9)
	(= (duration-association-reaction pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 1.1)
	(= (duration-association-reaction pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 1.1)
	(= (duration-association-reaction pRb E2F4-DP12 pRb-E2F4-DP12) 1.1)
	(= (duration-synthesis-reaction pRb-Jun-c-Fos-gERCC1 ERCC1) 3.4)
	(= (duration-association-reaction pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1) 1.1)
	(= (duration-association-reaction pRb-Jun c-Fos pRb-Jun-c-Fos) 0.8)
	(= (duration-association-reaction pRb Jun pRb-Jun) 1.0)
	(= (duration-catalyzed-association-reaction pRbp1 cdk2p2-cycEp1 pRbp1p2) 2.3)
	(= (duration-catalyzed-association-reaction pRbp1 cdk2p2-cycE pRbp1p2) 2.3)
	(= (duration-association-reaction pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 1.0)
	(= (duration-association-reaction pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 0.8)
	(= (duration-association-reaction pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 1.0)
	(= (duration-association-reaction pRbp1 E2F4-DP12 pRbp1-E2F4-DP12) 0.9)
	(= (duration-synthesis-reaction pRbp1-Jun-c-Fos-gERCC1 ERCC1) 3.4)
	(= (duration-association-reaction pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1) 0.9)
	(= (duration-association-reaction pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 0.9)
	(= (duration-association-reaction pRbp1 Jun pRbp1-Jun) 0.9)
	(= (duration-synthesis-reaction pRbp1p2-Jun-c-Fos-gERCC1 ERCC1) 4.4)
	(= (duration-association-reaction pRbp1p2-Jun-c-Fos gERCC1 pRbp1p2-Jun-c-Fos-gERCC1) 1.1)
	(= (duration-association-reaction pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos) 0.8)
	(= (duration-association-reaction pRbp1p2 Jun pRbp1p2-Jun) 0.9)
	(= (duration-catalyzed-association-reaction pRbp2 cdk46p3-cycDp1 pRbp1p2) 1.8)
	(= (duration-catalyzed-association-reaction pRbp2 cdk46p3-cycD pRbp1p2) 2.3)
	(= (duration-synthesis-reaction pRbp2-Jun-c-Fos-gERCC1 ERCC1) 3.3)
	(= (duration-association-reaction pRbp2-Jun-c-Fos gERCC1 pRbp2-Jun-c-Fos-gERCC1) 1.0)
	(= (duration-association-reaction pRbp2-Jun c-Fos pRbp2-Jun-c-Fos) 1.1)
	(= (duration-association-reaction pRbp2 Jun pRbp2-Jun) 0.9)
	(= (duration-association-reaction RPA cycA RPA-cycA) 1.1)
	(= (duration-catalyzed-association-reaction Skp1 cdk2p2-cycA Skp1p1) 1.9)
	(= (duration-association-reaction Skp2 cdk2-cycA Skp2-cdk2-cycA) 0.8)
	(= (duration-association-reaction Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA) 0.9)
	(= (duration-association-reaction Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA) 1.1)
	(= (duration-association-reaction Skp2 cdk2p2-cycA Skp2-cdk2p2-cycA) 1.1)
	(= (duration-catalyzed-association-reaction Skp2 cdk2p2-cycA Skp2p1) 2.1)
	(= (duration-association-reaction Skp2p1 Skp1p1 Skp2p1-Skp1p1) 1.1)
	(= (duration-association-reaction Skp2p1 Skp1 Skp2p1-Skp1) 0.8)
	(= (duration-association-reaction Skp2-Skp1 cdk2-cycA Skp2-Skp1-cdk2-cycA) 1.1)
	(= (duration-association-reaction Skp2-Skp1 cdk2p1-cycA Skp2-Skp1-cdk2p1-cycA) 0.9)
	(= (duration-association-reaction Skp2-Skp1 cdk2p1p2-cycA Skp2-Skp1-cdk2p1p2-cycA) 1.0)
	(= (duration-association-reaction Skp2-Skp1 cdk2p2-cycA Skp2-Skp1-cdk2p2-cycA) 0.9)
	(= (duration-association-reaction Skp2-Skp1p1 cdk2-cycA Skp2-Skp1p1-cdk2-cycA) 0.9)
	(= (duration-association-reaction Skp2-Skp1p1 cdk2p1-cycA Skp2-Skp1p1-cdk2p1-cycA) 0.9)
	(= (duration-association-reaction Skp2-Skp1p1 cdk2p1p2-cycA Skp2-Skp1p1-cdk2p1p2-cycA) 0.9)
	(= (duration-association-reaction Skp2-Skp1p1 cdk2p2-cycA Skp2-Skp1p1-cdk2p2-cycA) 0.9)
	(= (duration-association-reaction Skp2 Skp1p1 Skp2-Skp1p1) 0.9)
	(= (duration-association-reaction Skp2 Skp1 Skp2-Skp1) 1.1)
	(= (duration-synthesis-reaction SP1-gP c-Myc) 4.2)
	(= (duration-synthesis-reaction SP1-gP cycA) 3.4)
	(= (duration-synthesis-reaction SP1-gP cycD) 4.3)
	(= (duration-synthesis-reaction SP1-gP cycDp1) 3.4)
	(= (duration-synthesis-reaction SP1-gP cycE) 3.5)
	(= (duration-synthesis-reaction SP1-gP cycEp1) 3.4)
	(= (duration-synthesis-reaction SP1-gP p107) 4.4)
	(= (duration-synthesis-reaction SP1-gP p107p1) 4.1)
	(= (duration-synthesis-reaction SP1-gP p19ARF) 3.5)
	(= (duration-synthesis-reaction SP1-gP pol) 3.8)
	(= (duration-association-reaction SP1 gP SP1-gP) 1.1)
	(= (duration-association-reaction SP1-p107 gP SP1-p107-gP) 1.1)
	(= (duration-association-reaction SP1-p107p1 gP SP1-p107p1-gP) 1.0)
	(= (duration-association-reaction SP1 p107p1 SP1-p107p1) 1.1)
	(= (duration-association-reaction SP1 p107 SP1-p107) 1.0))

(:goal
	(and
	(preference p0A (>= (+ (available p68p1p2) (available Skp2-Skp1p1-cdk2-cycA)) 5))
	(preference p0B (>= (+ (available Skp2-Skp1p1-cdk2p1p2-cycA) (available Skp2-Skp1p1-cdk2p2-cycA)) 4))
	(preference p0C (>= (+ (available Skp2-Skp1p1-cdk2p1-cycA) (available Skp2-Skp1p1)) 5))
	(preference p0D (>= (+ (available p53p1-DP12p1) (available Skp2p1-Skp1p1)) 3))
	(preference p0E (>= (+ (available p21-cdk2p1p2-cycEp1) (available Skp2p1-Skp1)) 7))
	(preference p0F (>= (+ (available p53-DP12p1) (available p21-cdk2p1-cycE)) 8))
	(preference p0G (>= (+ (available Skp2-Skp1-cdk2-cycA) (available cdk2p1p2-cycE)) 5))
	(preference p0H (>= (+ (available p21-cdk46p1p2-cycD) (available Mdm2-pRbp1p2)) 4))
	(preference p0I (>= (+ (available cdk2p1p2-cycA) (available pRbp1p2-Jun-c-Fos-gERCC1)) 3))
	(preference p0J (>= (+ (available ERCC1) (available HDAC1-pRb-E2F13p1-DP12p1)) 5))
	(preference p0K (>= (+ (available Skp2-Skp1-cdk2p1p2-cycA) (available Jun-c-Fos-gERCC1)) 5))
	(preference p0L (>= (+ (available p21-cdk2p1-cycEp1) (available SP1-p107p1-gP)) 6))))


(:constraints (and

	(preference p1A (sometime-before (> (available Skp2-Skp1p1-cdk2-cycA) 0) (> (available cdk2p2-cycA) 0)))
	(preference p1B (sometime-before (> (available Skp2-Skp1p1-cdk2p1-cycA) 0) (> (available Skp2-Skp1p1) 0)))
	(preference p1C (sometime-before (> (available cdk2p1p2-cycA) 0) (> (available cdk2p1p2) 0)))
	(preference p1D (sometime-before (> (available ERCC1) 0) (> (available pRbp1p2-Jun-c-Fos) 0)))
	(preference p1E (sometime-before (> (available Skp2-Skp1-cdk2p1p2-cycA) 0) (> (available Skp2-Skp1) 0)))
	(preference p1F (sometime-before (> (available Jun-c-Fos-gERCC1) 0) (> (available Jun-c-Fos) 0)))

	(preference p1G (always (= (available Skp2p1) 0)))

	(preference p1H (sometime (> (available p19ARF) 0)))
	(preference p1I (sometime-after (> (available p19ARF) 0) (> (available cdk2p1-cycE) 0)))
	(preference p1J (sometime (> (available E2F2-DP12) 0)))
	(preference p1K (sometime-after (> (available E2F2-DP12) 0) (> (available CEBP-pRbp1-gP) 0)))
	(preference p1L (sometime (> (available pRbp1-E2F13p1-DP12p1) 0)))
	(preference p1M (sometime-after (> (available pRbp1-E2F13p1-DP12p1) 0) (> (available pRb-E2F13-DP12) 0)))
	(preference p1N (sometime (> (available cdk2p1-cycA) 0)))
	(preference p1O (sometime-after (> (available cdk2p1-cycA) 0) (> (available cdk2-cycE) 0)))
	(preference p1P (sometime (> (available E2F3-DP12) 0)))
	(preference p1Q (sometime-after (> (available E2F3-DP12) 0) (> (available HDAC1-p107-E2F4-DP12) 0)))
	(preference p1R (sometime (> (available pol) 0)))
	(preference p1S (sometime-after (> (available pol) 0) (> (available cdk7p1) 0)))
	(preference p1T (sometime (> (available SP1-p107p1) 0)))
	(preference p1U (sometime-after (> (available SP1-p107p1) 0) (> (available cdk1p1p2p3-Gadd45) 0)))))

(:metric minimize (+ (* 2.3 (is-violated p0A))
		     (* 2.3 (is-violated p0B))
		     (* 2.2 (is-violated p0C))
		     (* 2.2 (is-violated p0D))
		     (* 2.3 (is-violated p0E))
		     (* 2.1 (is-violated p0F))
		     (* 2.2 (is-violated p0G))
		     (* 2.3 (is-violated p0H))
		     (* 2.3 (is-violated p0I))
		     (* 2.2 (is-violated p0J))
		     (* 2.2 (is-violated p0K))
		     (* 1.4 (is-violated p0L))
		     (* 1 (is-violated p1A))
		     (* 1 (is-violated p1B))
		     (* 1 (is-violated p1C))
		     (* 1 (is-violated p1D))
		     (* 1 (is-violated p1E))
		     (* 1 (is-violated p1F))
		     (* 1 (is-violated p1G))
		     (* 1 (is-violated p1H))
		     (* 1 (is-violated p1I))
		     (* 1 (is-violated p1J))
		     (* 1 (is-violated p1K))
		     (* 1 (is-violated p1L))
		     (* 1 (is-violated p1M))
		     (* 1 (is-violated p1N))
		     (* 1 (is-violated p1O))
		     (* 1 (is-violated p1P))
		     (* 1 (is-violated p1Q))
		     (* 1 (is-violated p1R))
		     (* 1 (is-violated p1S))
		     (* 1 (is-violated p1T))
		     (* 1 (is-violated p1U))
		     (* 0.01 (total-time))
		     (num-subs)))

)
